Nonstop flights from Knoxville TYS
You can fly nonstop from Mc Ghee Tyson (TYS) to 41 destinations in 1 country, on 6 airlines. The airlines with the most nonstop routes here are Allegiant Air (21), American Airlines (10) and Southwest Airlines (9). The longest is Las Vegas (LAS), 1,735 miles (2,793 km).
Filter these routes in RoutesAll 41 nonstop destinations from TYS
Pick one for every airline on the route, the 1-stop connections and which points programs can book it.
North America 路 41
- Atlanta ATLUnited States 路 152 mi

- Austin AUSUnited States 路 881 mi

+1
- Baltimore BWIUnited States 路 464 mi

- Baton Rouge BTRUnited States 路 552 mi

- Bentonville XNAUnited States 路 577 mi

- Birmingham BHMUnited States 路 221 mi

- Boston BOSUnited States 路 829 mi

- Charlotte CLTUnited States 路 176 mi

- Chicago MDWUnited States 路 460 mi

- Chicago ORDUnited States 路 475 mi


- College Station CLLUnited States 路 800 mi

- Dallas DALUnited States 路 761 mi

- Dallas DFWUnited States 路 770 mi

- Denver DENUnited States 路 1,160 mi



- Detroit DTWUnited States 路 444 mi

- Dulles IADUnited States 路 419 mi


- Fort Lauderdale FLLUnited States 路 710 mi

- Fort Walton Beach VPSUnited States 路 396 mi

- Gulf Shores GUFUnited States 路 437 mi

- Houston HOUUnited States 路 781 mi

- Houston IAHUnited States 路 771 mi

- Jacksonville JAXUnited States 路 391 mi

- Key West EYWUnited States 路 789 mi

- Las Vegas LASUnited States 路 1,735 mi


- Memphis MEMUnited States 路 341 mi

- Miami MIAUnited States 路 726 mi

- Minneapolis MSPUnited States 路 792 mi

- Nashville BNAUnited States 路 152 mi

- New Haven HVNUnited States 路 708 mi

- New Orleans MSYUnited States 路 542 mi


- New York EWRUnited States 路 629 mi


- New York LGAUnited States 路 647 mi


- Orlando MCOUnited States 路 533 mi


- Orlando SFBUnited States 路 511 mi

- Philadelphia PHLUnited States 路 554 mi


- Phoenix PHXUnited States 路 1,596 mi

- Punta Gorda PGDUnited States 路 625 mi

- Saint Petersburg PIEUnited States 路 551 mi

- Sarasota SRQUnited States 路 588 mi

- Tampa TPAUnited States 路 547 mi

- Washington DCAUnited States 路 436 mi


Airlines flying from TYS
oneworld: 10 destinations 路 SkyTeam: 8 destinations 路 Star Alliance: 6 destinations
- Allegiant Air21 routes

- American Airlinesoneworld10 routes

- Southwest Airlines9 routes

- Delta Air LinesSkyTeam8 routes

- United AirlinesStar Alliance6 routes

- Avelo Airlines1 route

Flights from TYS: common questions
How many nonstop destinations are there from TYS?
41 destinations in 1 country have a nonstop flight from Mc Ghee Tyson (TYS), flown by 6 airlines. Pick any of them on this page to see every airline on the route and the 1-stop connections.
Which airlines fly from TYS?
6 airlines fly nonstop from TYS. By number of destinations: Allegiant Air (21), American Airlines (10), Southwest Airlines (9), Delta Air Lines (8), United Airlines (6) and Avelo Airlines (1).
What is the longest nonstop flight from TYS?
Knoxville (TYS) to Las Vegas (LAS), on Allegiant Air and Southwest Airlines, at about 1,735 miles (2,793 km) as the crow flies. Next is Phoenix (PHX), about 1,596 miles (2,568 km).
Which airline alliance has the most routes from TYS?
oneworld airlines fly to 10 destinations, SkyTeam airlines fly to 8 destinations and Star Alliance airlines fly to 6 destinations nonstop from TYS. The rest are flown only by airlines outside the three alliances.
More airports in the United States
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.