Knoxville (TYS) to Charlotte (CLT) flights
One airline flies nonstop from Knoxville (TYS) to Charlotte (CLT): American Airlines. The two airports are 176 miles (284 km) apart. American Airlines is in oneworld. There are also 15 ways to fly it with one stop, through Atlanta, Nashville and Birmingham and more.
Airlines flying nonstop from TYS to CLT
- American Airlinesoneworld · bookable with 9 programsWho books it

Book TYS to CLT with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Alaska Atmos RewardsBooks American Airlines
- American AAdvantageBooks American Airlines
- British Airways ClubBooks American Airlines
- Cathay Pacific Asia MilesBooks American Airlines
- Finnair PlusBooks American Airlines
- Iberia ClubBooks American Airlines
- JAL Mileage BankBooks American Airlines
- Qantas Frequent FlyerBooks American Airlines
- Qatar Airways Privilege ClubBooks American Airlines
TYS to CLT with one stop
15 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Atlanta (ATL)Delta Air Lines the whole way



- Via Nashville (BNA)Southwest Airlines the whole way



- Via Birmingham (BHM)United Airlines, then American Airlines


- Via Jacksonville (JAX)Allegiant Air, then American Airlines


- Via Dulles (IAD)United Airlines the whole way




- Via Washington (DCA)American Airlines the whole way



- Via Baltimore (BWI)Southwest Airlines the whole way




- Via Memphis (MEM)Allegiant Air, then American Airlines


- Via Fort Walton Beach (VPS)Allegiant Air, then American Airlines


- Via Detroit (DTW)Delta Air Lines the whole way



- Via Orlando (MCO)Allegiant Air and Southwest Airlines, then American Airlines and Frontier Airlines




- Via Philadelphia (PHL)American Airlines the whole way




- Via Chicago (MDW)Allegiant Air, then Southwest Airlines


- Via Tampa (TPA)Southwest Airlines, then American Airlines


- Via Chicago (ORD)American Airlines and United Airlines the whole way




TYS to CLT: common questions
Which airlines fly nonstop from TYS to CLT?
American Airlines (oneworld) flies nonstop from Knoxville (TYS) to Charlotte (CLT).
How far is Knoxville from Charlotte by plane?
Knoxville (TYS) and Charlotte (CLT) are 176 miles (284 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book TYS to CLT award flights?
9 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, American AAdvantage, British Airways Club, Cathay Pacific Asia Miles, Finnair Plus, Iberia Club, JAL Mileage Bank, Qantas Frequent Flyer and 1 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does TYS to CLT cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for TYS to CLT with taxes and fees.
Where can I connect between Knoxville and Charlotte?
The most direct connections are through Atlanta (ATL), Nashville (BNA), Birmingham (BHM), Jacksonville (JAX) and Dulles (IAD). On 8 of them the same airline flies both flights, for example Delta Air Lines through Atlanta.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.