Knoxville (TYS) to Detroit (DTW) flights
One airline flies nonstop from Knoxville (TYS) to Detroit (DTW): Delta Air Lines. The two airports are 444 miles (714 km) apart. Delta Air Lines is in SkyTeam. There are also 17 ways to fly it with one stop, through Nashville, Charlotte and Chicago and more.
Airlines flying nonstop from TYS to DTW
- Delta Air LinesSkyTeam · bookable with 8 programsWho books it

Book TYS to DTW with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Aeromexico RewardsBooks Delta Air Lines
- Air France-KLM Flying BlueBooks Delta Air Lines
- China Eastern Eastern MilesBooks Delta Air Lines
- Delta SkyMilesBooks Delta Air Lines
- Garuda Indonesia GarudaMilesBooks Delta Air Lines
- Korean Air SKYPASSBooks Delta Air Lines
- SAS EuroBonusBooks Delta Air Lines
- Virgin Atlantic Flying ClubBooks Delta Air Lines
TYS to DTW with one stop
17 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way



- Via Charlotte (CLT)American Airlines the whole way



- Via Chicago (MDW)Allegiant Air, then Delta Air Lines and Southwest Airlines



- Via Chicago (ORD)American Airlines and United Airlines the whole way





- Via Atlanta (ATL)Delta Air Lines the whole way



- Via Dulles (IAD)United Airlines the whole way




- Via Washington (DCA)American Airlines and Delta Air Lines the whole way




- Via Birmingham (BHM)United Airlines, then Delta Air Lines


- Via Baltimore (BWI)Southwest Airlines the whole way




- Via Memphis (MEM)Allegiant Air, then Delta Air Lines


- Via Philadelphia (PHL)American Airlines the whole way





- Via New York (EWR)United Airlines the whole way




- Via New York (LGA)Delta Air Lines and American Airlines the whole way




- Via Jacksonville (JAX)Allegiant Air, then Delta Air Lines


- Via New Haven (HVN)Avelo Airlines the whole way


TYS to DTW: common questions
Which airlines fly nonstop from TYS to DTW?
Delta Air Lines (SkyTeam) flies nonstop from Knoxville (TYS) to Detroit (DTW).
How far is Knoxville from Detroit by plane?
Knoxville (TYS) and Detroit (DTW) are 444 miles (714 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book TYS to DTW award flights?
8 programs can book at least one of the nonstop airlines: Aeromexico Rewards, Air France-KLM Flying Blue, China Eastern Eastern Miles, Delta SkyMiles, Garuda Indonesia GarudaMiles, Korean Air SKYPASS, SAS EuroBonus and Virgin Atlantic Flying Club. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does TYS to DTW cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for TYS to DTW with taxes and fees.
Where can I connect between Knoxville and Detroit?
The most direct connections are through Nashville (BNA), Charlotte (CLT), Chicago (MDW), Chicago (ORD) and Atlanta (ATL). On 13 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.