Knoxville (TYS) to Memphis (MEM) flights
One airline flies nonstop from Knoxville (TYS) to Memphis (MEM): Allegiant Air. The two airports are 341 miles (549 km) apart. There are also 17 ways to fly it with one stop, through Nashville, Atlanta and Charlotte and more.
Airlines flying nonstop from TYS to MEM
- Allegiant AirNot in an alliance

TYS to MEM with one stop
17 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way


- Via Atlanta (ATL)Delta Air Lines the whole way


- Via Charlotte (CLT)American Airlines the whole way


- Via New Orleans (MSY)American Airlines the whole way



- Via Chicago (MDW)Allegiant Air, then Southwest Airlines


- Via Chicago (ORD)American Airlines and United Airlines the whole way




- Via Detroit (DTW)Delta Air Lines the whole way


- Via Orlando (SFB)Allegiant Air the whole way


- Via Dallas (DAL)Southwest Airlines the whole way


- Via Washington (DCA)American Airlines and Delta Air Lines the whole way




- Via Tampa (TPA)Southwest Airlines the whole way



- Via Saint Petersburg (PIE)Allegiant Air the whole way


- Via Dallas (DFW)American Airlines the whole way


- Via Orlando (MCO)Southwest Airlines the whole way




- Via Houston (IAH)United Airlines the whole way


TYS to MEM: common questions
Which airlines fly nonstop from TYS to MEM?
Allegiant Air flies nonstop from Knoxville (TYS) to Memphis (MEM).
How far is Knoxville from Memphis by plane?
Knoxville (TYS) and Memphis (MEM) are 341 miles (549 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does TYS to MEM cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for TYS to MEM with taxes and fees.
Where can I connect between Knoxville and Memphis?
The most direct connections are through Nashville (BNA), Atlanta (ATL), Charlotte (CLT), New Orleans (MSY) and Chicago (MDW). On 15 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.