Knoxville (TYS) to Key West (EYW) flights
One airline flies nonstop from Knoxville (TYS) to Key West (EYW): Allegiant Air. The two airports are 789 miles (1,269 km) apart. There are also 11 ways to fly it with one stop, through Tampa, Saint Petersburg and Atlanta and more.
Airlines flying nonstop from TYS to EYW
- Allegiant AirNot in an alliance
TYS to EYW with one stop
11 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Tampa (TPA)Southwest Airlines, then Breeze Airways
- Via Saint Petersburg (PIE)Allegiant Air the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Orlando (MCO)Allegiant Air and Southwest Airlines, then Breeze Airways
- Via Orlando (SFB)Allegiant Air the whole way
- Via Miami (MIA)American Airlines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Dulles (IAD)United Airlines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Philadelphia (PHL)American Airlines the whole way
- Via Houston (IAH)United Airlines the whole way
TYS to EYW: common questions
Which airlines fly nonstop from TYS to EYW?
Allegiant Air flies nonstop from Knoxville (TYS) to Key West (EYW).
How far is Knoxville from Key West by plane?
Knoxville (TYS) and Key West (EYW) are 789 miles (1,269 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does TYS to EYW cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for TYS to EYW with taxes and fees.
Where can I connect between Knoxville and Key West?
The most direct connections are through Tampa (TPA), Saint Petersburg (PIE), Atlanta (ATL), Orlando (MCO) and Orlando (SFB). On 9 of them the same airline flies both flights, for example Allegiant Air through Saint Petersburg.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.