Key West (EYW) to Knoxville (TYS) flights
One airline flies nonstop from Key West (EYW) to Knoxville (TYS): Allegiant Air. The two airports are 789 miles (1,269 km) apart. There are also 11 ways to fly it with one stop, through Tampa, Saint Petersburg and Atlanta and more.
Airlines flying nonstop from EYW to TYS
- Allegiant AirNot in an alliance
EYW to TYS with one stop
11 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Tampa (TPA)Breeze Airways, then Southwest Airlines
- Via Saint Petersburg (PIE)Allegiant Air the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Orlando (MCO)Breeze Airways, then Allegiant Air and Southwest Airlines
- Via Orlando (SFB)Allegiant Air the whole way
- Via Miami (MIA)American Airlines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Dulles (IAD)United Airlines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Philadelphia (PHL)American Airlines the whole way
- Via Houston (IAH)United Airlines the whole way
EYW to TYS: common questions
Which airlines fly nonstop from EYW to TYS?
Allegiant Air flies nonstop from Key West (EYW) to Knoxville (TYS).
How far is Key West from Knoxville by plane?
Key West (EYW) and Knoxville (TYS) are 789 miles (1,269 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does EYW to TYS cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for EYW to TYS with taxes and fees.
Where can I connect between Key West and Knoxville?
The most direct connections are through Tampa (TPA), Saint Petersburg (PIE), Atlanta (ATL), Orlando (MCO) and Orlando (SFB). On 9 of them the same airline flies both flights, for example Allegiant Air through Saint Petersburg.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.