Saint Louis (STL) to San Diego (SAN) flights
One airline flies nonstop from Saint Louis (STL) to San Diego (SAN): Southwest Airlines. The two airports are 1,554 miles (2,501 km) apart. There are also 38 ways to fly it with one stop, through Phoenix, Kansas City and Denver and more.
Airlines flying nonstop from STL to SAN
- Southwest AirlinesNot in an allianceWho books it
STL to SAN with one stop
38 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Phoenix (PHX)American Airlines and Southwest Airlines the whole way
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- Via Kansas City (MCI)Southwest Airlines the whole way
- Via Denver (DEN)Frontier Airlines, United Airlines and 1 more the whole way
+1 - Via Las Vegas (LAS)Frontier Airlines and Southwest Airlines the whole way
+1 - Via Omaha (OMA)Southwest Airlines the whole way
- Via Los Angeles (LAX)American Airlines and Southwest Airlines, then Delta Air Lines and United Airlines
- Via Dallas (DFW)American Airlines and Frontier Airlines the whole way
- Via Dallas (DAL)Southwest Airlines the whole way
- Via Salt Lake City (SLC)Delta Air Lines the whole way
- Via Austin (AUS)Southwest Airlines the whole way
- Via San Antonio (SAT)Southwest Airlines the whole way
- Via Houston (IAH)United Airlines the whole way
- Via Minneapolis (MSP)Delta Air Lines the whole way
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
STL to SAN: common questions
Which airlines fly nonstop from STL to SAN?
Southwest Airlines flies nonstop from Saint Louis (STL) to San Diego (SAN).
How far is Saint Louis from San Diego by plane?
Saint Louis (STL) and San Diego (SAN) are 1,554 miles (2,501 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does STL to SAN cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for STL to SAN with taxes and fees.
Where can I connect between Saint Louis and San Diego?
The most direct connections are through Phoenix (PHX), Kansas City (MCI), Denver (DEN), Las Vegas (LAS) and Omaha (OMA). On 34 of them the same airline flies both flights, for example American Airlines through Phoenix.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.