San Diego (SAN) to Saint Louis (STL) flights
One airline flies nonstop from San Diego (SAN) to Saint Louis (STL): Southwest Airlines. The two airports are 1,554 miles (2,501 km) apart. There are also 38 ways to fly it with one stop, through Phoenix, Kansas City and Denver and more.
Airlines flying nonstop from SAN to STL
- Southwest AirlinesNot in an allianceWho books it
SAN to STL with one stop
38 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Phoenix (PHX)American Airlines and Southwest Airlines the whole way
+1
- Via Kansas City (MCI)Southwest Airlines the whole way
- Via Denver (DEN)Frontier Airlines, United Airlines and 1 more the whole way
+1 - Via Las Vegas (LAS)Southwest Airlines and Frontier Airlines the whole way
+1 - Via Omaha (OMA)Southwest Airlines the whole way
- Via Los Angeles (LAX)Delta Air Lines and United Airlines, then American Airlines and Southwest Airlines
- Via Dallas (DFW)American Airlines and Frontier Airlines the whole way
- Via Dallas (DAL)Southwest Airlines the whole way
- Via Salt Lake City (SLC)Delta Air Lines the whole way
- Via Austin (AUS)Southwest Airlines the whole way
- Via San Antonio (SAT)Southwest Airlines the whole way
- Via Houston (IAH)United Airlines the whole way
- Via Minneapolis (MSP)Delta Air Lines the whole way
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
SAN to STL: common questions
Which airlines fly nonstop from SAN to STL?
Southwest Airlines flies nonstop from San Diego (SAN) to Saint Louis (STL).
How far is San Diego from Saint Louis by plane?
San Diego (SAN) and Saint Louis (STL) are 1,554 miles (2,501 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does SAN to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for SAN to STL with taxes and fees.
Where can I connect between San Diego and Saint Louis?
The most direct connections are through Phoenix (PHX), Kansas City (MCI), Denver (DEN), Las Vegas (LAS) and Omaha (OMA). On 34 of them the same airline flies both flights, for example American Airlines through Phoenix.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.