Saint Louis (STL) to Myrtle Beach (MYR) flights
One airline flies nonstop from Saint Louis (STL) to Myrtle Beach (MYR): Southwest Airlines. The two airports are 728 miles (1,171 km) apart. There are also 18 ways to fly it with one stop, through Charlotte, Nashville and Atlanta and more.
Airlines flying nonstop from STL to MYR
- Southwest AirlinesNot in an allianceWho books it

STL to MYR with one stop
18 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Charlotte (CLT)American Airlines the whole way



- Via Nashville (BNA)Southwest Airlines the whole way


- Via Atlanta (ATL)Delta Air Lines the whole way




- Via Chicago (MDW)Southwest Airlines the whole way


- Via Chicago (ORD)American Airlines and United Airlines the whole way




- Via Pittsburgh (PIT)Southwest Airlines the whole way




- Via Dulles (IAD)United Airlines the whole way


- Via Detroit (DTW)Delta Air Lines the whole way



- Via Washington (DCA)American Airlines the whole way



- Via Baltimore (BWI)Southwest Airlines the whole way


- Via Orlando (MCO)Frontier Airlines and Southwest Airlines, then Breeze Airways



- Via Philadelphia (PHL)American Airlines the whole way




- Via Tampa (TPA)Southwest Airlines, then Breeze Airways


- Via New York (EWR)United Airlines the whole way


- Via New York (LGA)American Airlines and Delta Air Lines the whole way





STL to MYR: common questions
Which airlines fly nonstop from STL to MYR?
Southwest Airlines flies nonstop from Saint Louis (STL) to Myrtle Beach (MYR).
How far is Saint Louis from Myrtle Beach by plane?
Saint Louis (STL) and Myrtle Beach (MYR) are 728 miles (1,171 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does STL to MYR cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for STL to MYR with taxes and fees.
Where can I connect between Saint Louis and Myrtle Beach?
The most direct connections are through Charlotte (CLT), Nashville (BNA), Atlanta (ATL), Chicago (MDW) and Chicago (ORD). On 15 of them the same airline flies both flights, for example American Airlines through Charlotte.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.