Myrtle Beach (MYR) to Saint Louis (STL) flights
One airline flies nonstop from Myrtle Beach (MYR) to Saint Louis (STL): Southwest Airlines. The two airports are 728 miles (1,171 km) apart. There are also 18 ways to fly it with one stop, through Charlotte, Nashville and Atlanta and more.
Airlines flying nonstop from MYR to STL
- Southwest AirlinesNot in an allianceWho books it
MYR to STL with one stop
18 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Charlotte (CLT)American Airlines the whole way
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Pittsburgh (PIT)Southwest Airlines the whole way
- Via Dulles (IAD)United Airlines the whole way
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Baltimore (BWI)Southwest Airlines the whole way
- Via Orlando (MCO)Breeze Airways, then Frontier Airlines and Southwest Airlines
- Via Philadelphia (PHL)American Airlines the whole way
- Via Tampa (TPA)Breeze Airways, then Southwest Airlines
- Via New York (EWR)United Airlines the whole way
- Via New York (LGA)American Airlines and Delta Air Lines the whole way
MYR to STL: common questions
Which airlines fly nonstop from MYR to STL?
Southwest Airlines flies nonstop from Myrtle Beach (MYR) to Saint Louis (STL).
How far is Myrtle Beach from Saint Louis by plane?
Myrtle Beach (MYR) and Saint Louis (STL) are 728 miles (1,171 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does MYR to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MYR to STL with taxes and fees.
Where can I connect between Myrtle Beach and Saint Louis?
The most direct connections are through Charlotte (CLT), Nashville (BNA), Atlanta (ATL), Chicago (MDW) and Chicago (ORD). On 15 of them the same airline flies both flights, for example American Airlines through Charlotte.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.