Saint Louis (STL) to Panama City (ECP) flights
One airline flies nonstop from Saint Louis (STL) to Panama City (ECP): Southwest Airlines. The two airports are 636 miles (1,023 km) apart. There are also 15 ways to fly it with one stop, through Nashville, Atlanta and Charlotte and more.
Airlines flying nonstop from STL to ECP
- Southwest AirlinesNot in an allianceWho books it
STL to ECP with one stop
15 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Kansas City (MCI)Southwest Airlines the whole way
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Columbus (CMH)Southwest Airlines the whole way
- Via Milwaukee (MKE)Southwest Airlines the whole way
- Via Dallas (DAL)Southwest Airlines the whole way
- Via Dallas (DFW)American Airlines the whole way
- Via Houston (IAH)United Airlines the whole way
- Via Houston (HOU)Southwest Airlines the whole way
- Via Austin (AUS)Southwest Airlines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Baltimore (BWI)Southwest Airlines the whole way
STL to ECP: common questions
Which airlines fly nonstop from STL to ECP?
Southwest Airlines flies nonstop from Saint Louis (STL) to Panama City (ECP).
How far is Saint Louis from Panama City by plane?
Saint Louis (STL) and Panama City (ECP) are 636 miles (1,023 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does STL to ECP cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for STL to ECP with taxes and fees.
Where can I connect between Saint Louis and Panama City?
The most direct connections are through Nashville (BNA), Atlanta (ATL), Charlotte (CLT), Kansas City (MCI) and Chicago (MDW). On 15 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.