Panama City (ECP) to Saint Louis (STL) flights
One airline flies nonstop from Panama City (ECP) to Saint Louis (STL): Southwest Airlines. The two airports are 636 miles (1,023 km) apart. There are also 15 ways to fly it with one stop, through Nashville, Atlanta and Charlotte and more.
Airlines flying nonstop from ECP to STL
- Southwest AirlinesNot in an allianceWho books it
ECP to STL with one stop
15 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Kansas City (MCI)Southwest Airlines the whole way
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Columbus (CMH)Southwest Airlines the whole way
- Via Milwaukee (MKE)Southwest Airlines the whole way
- Via Dallas (DAL)Southwest Airlines the whole way
- Via Dallas (DFW)American Airlines the whole way
- Via Houston (IAH)United Airlines the whole way
- Via Houston (HOU)Southwest Airlines the whole way
- Via Austin (AUS)Southwest Airlines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Baltimore (BWI)Southwest Airlines the whole way
ECP to STL: common questions
Which airlines fly nonstop from ECP to STL?
Southwest Airlines flies nonstop from Panama City (ECP) to Saint Louis (STL).
How far is Panama City from Saint Louis by plane?
Panama City (ECP) and Saint Louis (STL) are 636 miles (1,023 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does ECP to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for ECP to STL with taxes and fees.
Where can I connect between Panama City and Saint Louis?
The most direct connections are through Nashville (BNA), Atlanta (ATL), Charlotte (CLT), Kansas City (MCI) and Chicago (MDW). On 15 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.