Chile to Colombia · 2,751 miles (4,427 km)

Santiago (SCL) to Medellin (MDE) flights

One airline flies nonstop from Santiago (SCL) to Medellin (MDE): JetSMART. The two airports are 2,751 miles (4,427 km) apart. There are also 10 ways to fly it with one stop, through Cali, Bogota and Lima and more.

Airlines flying nonstop from SCL to MDE

  • JetSMART logo
    JetSMARTNot in an alliance

SCL to MDE with one stop

10 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.

  • Via Cali (CLO)JetSMART the whole way
    JetSMART logo
    AVIANCA logo
    LATAM Airlines logo
    JetSMART logo
  • Via Bogota (BOG)AVIANCA, LATAM Airlines and 1 more the whole way
    AVIANCA logo
    LATAM Airlines logo
    JetSMART logo
    AVIANCA logo
    LATAM Airlines logo
    P5
    +1
  • Via Lima (LIM)JetSMART and LATAM Airlines the whole way
    Sky Airline logo
    JetSMART logo
    LATAM Airlines logo
    LATAM Airlines logo
    JetSMART logo
  • Via Quito (UIO)LATAM Airlines, then AVIANCA
    LATAM Airlines logo
    AVIANCA logo
  • Via Guayaquil (GYE)LATAM Airlines, then AVIANCA
    LATAM Airlines logo
    AVIANCA logo
  • Via Panama City (PTY)Copa Airlines the whole way
    Copa Airlines logo
    Copa Airlines logo
  • Via Cartagena (CTG)AVIANCA the whole way
    AVIANCA logo
    AVIANCA logo
    P5
    JetSMART logo
    +1
  • Via Buenos Aires (EZE)Sky Airline, KLM and 1 more, then AVIANCA and JetSMART
    Sky Airline logo
    KLM logo
    LATAM Airlines logo
    AVIANCA logo
    JetSMART logo
  • Via Punta Cana (PUJ)Arajet the whole way
    LATAM Airlines logo
    Arajet logo
    Sky Airline logo
    AVIANCA logo
    P5
    Arajet logo
    +1
  • Via Cancun (CUN)LATAM Airlines, then AVIANCA and Wingo
    LATAM Airlines logo
    AVIANCA logo
    P5

SCL to MDE: common questions

Which airlines fly nonstop from SCL to MDE?

JetSMART flies nonstop from Santiago (SCL) to Medellin (MDE).

How far is Santiago from Medellin by plane?

Santiago (SCL) and Medellin (MDE) are 2,751 miles (4,427 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.

How many miles does SCL to MDE cost?

It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for SCL to MDE with taxes and fees.

Where can I connect between Santiago and Medellin?

The most direct connections are through Cali (CLO), Bogota (BOG), Lima (LIM), Quito (UIO) and Guayaquil (GYE). On 6 of them the same airline flies both flights, for example JetSMART through Cali.

More routes

Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.