Santiago (SCL) to Cali (CLO) flights
One airline flies nonstop from Santiago (SCL) to Cali (CLO): JetSMART. The two airports are 2,578 miles (4,149 km) apart. There are also 6 ways to fly it with one stop, through Antofagasta, Bogota and Medellin and more.
Airlines flying nonstop from SCL to CLO
- JetSMARTNot in an alliance

SCL to CLO with one stop
6 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Antofagasta (ANF)JetSMART the whole way




- Via Bogota (BOG)AVIANCA, LATAM Airlines and 1 more the whole way




P5+2 - Via Medellin (MDE)JetSMART the whole way




- Via Panama City (PTY)Copa Airlines the whole way


- Via Cartagena (CTG)AVIANCA the whole way




- Via Punta Cana (PUJ)LATAM Airlines, Arajet and 1 more, then JetSMART




SCL to CLO: common questions
Which airlines fly nonstop from SCL to CLO?
JetSMART flies nonstop from Santiago (SCL) to Cali (CLO).
How far is Santiago from Cali by plane?
Santiago (SCL) and Cali (CLO) are 2,578 miles (4,149 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does SCL to CLO cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for SCL to CLO with taxes and fees.
Where can I connect between Santiago and Cali?
The most direct connections are through Antofagasta (ANF), Bogota (BOG), Medellin (MDE), Panama City (PTY) and Cartagena (CTG). On 5 of them the same airline flies both flights, for example JetSMART through Antofagasta.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.