Cali (CLO) to Santiago (SCL) flights
One airline flies nonstop from Cali (CLO) to Santiago (SCL): JetSMART. The two airports are 2,578 miles (4,149 km) apart. There are also 6 ways to fly it with one stop, through Antofagasta, Bogota and Medellin and more.
Airlines flying nonstop from CLO to SCL
- JetSMARTNot in an alliance
CLO to SCL with one stop
6 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Antofagasta (ANF)JetSMART the whole way
- Via Bogota (BOG)AVIANCA, LATAM Airlines and 1 more the whole way
P5+2 - Via Medellin (MDE)JetSMART the whole way
- Via Panama City (PTY)Copa Airlines the whole way
- Via Cartagena (CTG)AVIANCA the whole way
- Via Punta Cana (PUJ)JetSMART, then LATAM Airlines, Arajet and 1 more
CLO to SCL: common questions
Which airlines fly nonstop from CLO to SCL?
JetSMART flies nonstop from Cali (CLO) to Santiago (SCL).
How far is Cali from Santiago by plane?
Cali (CLO) and Santiago (SCL) are 2,578 miles (4,149 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does CLO to SCL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for CLO to SCL with taxes and fees.
Where can I connect between Cali and Santiago?
The most direct connections are through Antofagasta (ANF), Bogota (BOG), Medellin (MDE), Panama City (PTY) and Cartagena (CTG). On 5 of them the same airline flies both flights, for example JetSMART through Antofagasta.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.