Panama City (PTY) to Medellin (MDE) flights
One airline flies nonstop from Panama City (PTY) to Medellin (MDE): Copa Airlines. The two airports are 337 miles (542 km) apart. Copa Airlines is in Star Alliance. There are also 12 ways to fly it with one stop, through Pereira, Cartagena and Bogota and more.
Airlines flying nonstop from PTY to MDE
- Copa AirlinesStar Alliance · bookable with 13 programsWho books it
Book PTY to MDE with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Air Canada AeroplanBooks Copa Airlines
- Air France-KLM Flying BlueBooks Copa Airlines
- Air New Zealand AirpointsBooks Copa Airlines
- ANA Mileage ClubBooks Copa Airlines
- Avianca LifeMilesBooks Copa Airlines
- Emirates SkywardsBooks Copa Airlines
- EVA Air Infinity MileageLandsBooks Copa Airlines
- Lufthansa Miles & MoreBooks Copa Airlines
- Singapore Airlines KrisFlyerBooks Copa Airlines
- TAP Miles&GoBooks Copa Airlines
- Thai Royal Orchid PlusBooks Copa Airlines
- Turkish Airlines Miles&SmilesBooks Copa Airlines
- United MileagePlusBooks Copa Airlines
PTY to MDE with one stop
12 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Pereira (PEI)Copa Airlines, then LATAM Airlines and AVIANCA
- Via Cartagena (CTG)Copa Airlines, then AVIANCA, Wingo and 2 moreP5+1
- Via Bogota (BOG)AVIANCA the whole wayP5+1
- Via Bucaramanga (BGA)Copa Airlines, then AVIANCA and WingoP5
- Via Cali (CLO)Copa Airlines, then AVIANCA, LATAM Airlines and 1 more
- Via Barranquilla (BAQ)Copa Airlines, then AVIANCA, LATAM Airlines and 2 moreP5+1
- Via Cucuta (CUC)Copa Airlines, then AVIANCA and JetSMART
- Via Santa Marta (SMR)Copa Airlines, then AVIANCA, Wingo and 1 moreP5
- Via San Andres Island (ADZ)Copa Airlines, then AVIANCA, LATAM Airlines and 1 more
- Via San Jose (SJO)AVIANCA the whole wayP5
- Via Quito (UIO)Copa Airlines, then AVIANCA
- Via Aruba (AUA)Copa Airlines, then WingoP5
PTY to MDE: common questions
Which airlines fly nonstop from PTY to MDE?
Copa Airlines (Star Alliance) flies nonstop from Panama City (PTY) to Medellin (MDE).
How far is Panama City from Medellin by plane?
Panama City (PTY) and Medellin (MDE) are 337 miles (542 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book PTY to MDE award flights?
13 programs can book at least one of the nonstop airlines: Air Canada Aeroplan, Air France-KLM Flying Blue, Air New Zealand Airpoints, ANA Mileage Club, Avianca LifeMiles, Emirates Skywards, EVA Air Infinity MileageLands, Lufthansa Miles & More and 5 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does PTY to MDE cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for PTY to MDE with taxes and fees.
Where can I connect between Panama City and Medellin?
The most direct connections are through Pereira (PEI), Cartagena (CTG), Bogota (BOG), Bucaramanga (BGA) and Cali (CLO). On 2 of them the same airline flies both flights, for example AVIANCA through Bogota.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.