Medellin (MDE) to Panama City (PTY) flights
One airline flies nonstop from Medellin (MDE) to Panama City (PTY): Copa Airlines. The two airports are 337 miles (542 km) apart. Copa Airlines is in Star Alliance. There are also 12 ways to fly it with one stop, through Pereira, Cartagena and Bogota and more.
Airlines flying nonstop from MDE to PTY
- Copa AirlinesStar Alliance · bookable with 13 programsWho books it
Book MDE to PTY with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Air Canada AeroplanBooks Copa Airlines
- Air France-KLM Flying BlueBooks Copa Airlines
- Air New Zealand AirpointsBooks Copa Airlines
- ANA Mileage ClubBooks Copa Airlines
- Avianca LifeMilesBooks Copa Airlines
- Emirates SkywardsBooks Copa Airlines
- EVA Air Infinity MileageLandsBooks Copa Airlines
- Lufthansa Miles & MoreBooks Copa Airlines
- Singapore Airlines KrisFlyerBooks Copa Airlines
- TAP Miles&GoBooks Copa Airlines
- Thai Royal Orchid PlusBooks Copa Airlines
- Turkish Airlines Miles&SmilesBooks Copa Airlines
- United MileagePlusBooks Copa Airlines
MDE to PTY with one stop
12 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Pereira (PEI)LATAM Airlines and AVIANCA, then Copa Airlines
- Via Cartagena (CTG)AVIANCA, Wingo and 2 more, then Copa AirlinesP5+1
- Via Bogota (BOG)AVIANCA the whole wayP5+1
- Via Bucaramanga (BGA)AVIANCA and Wingo, then Copa AirlinesP5
- Via Cali (CLO)AVIANCA, LATAM Airlines and 1 more, then Copa Airlines
- Via Barranquilla (BAQ)AVIANCA, LATAM Airlines and 2 more, then Copa AirlinesP5+1
- Via Cucuta (CUC)AVIANCA and JetSMART, then Copa Airlines
- Via Santa Marta (SMR)AVIANCA, Wingo and 1 more, then Copa AirlinesP5
- Via San Andres Island (ADZ)AVIANCA, LATAM Airlines and 1 more, then Copa Airlines
- Via San Jose (SJO)AVIANCA the whole wayP5
- Via Quito (UIO)AVIANCA, then Copa Airlines
- Via Aruba (AUA)Wingo, then Copa AirlinesP5
MDE to PTY: common questions
Which airlines fly nonstop from MDE to PTY?
Copa Airlines (Star Alliance) flies nonstop from Medellin (MDE) to Panama City (PTY).
How far is Medellin from Panama City by plane?
Medellin (MDE) and Panama City (PTY) are 337 miles (542 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book MDE to PTY award flights?
13 programs can book at least one of the nonstop airlines: Air Canada Aeroplan, Air France-KLM Flying Blue, Air New Zealand Airpoints, ANA Mileage Club, Avianca LifeMiles, Emirates Skywards, EVA Air Infinity MileageLands, Lufthansa Miles & More and 5 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does MDE to PTY cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MDE to PTY with taxes and fees.
Where can I connect between Medellin and Panama City?
The most direct connections are through Pereira (PEI), Cartagena (CTG), Bogota (BOG), Bucaramanga (BGA) and Cali (CLO). On 2 of them the same airline flies both flights, for example AVIANCA through Bogota.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.