Minneapolis (MSP) to Knoxville (TYS) flights
One airline flies nonstop from Minneapolis (MSP) to Knoxville (TYS): Delta Air Lines. The two airports are 792 miles (1,275 km) apart. Delta Air Lines is in SkyTeam. There are also 19 ways to fly it with one stop, through Chicago, Chicago and Nashville and more.
Airlines flying nonstop from MSP to TYS
- Delta Air LinesSkyTeam · bookable with 8 programsWho books it
Book MSP to TYS with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Aeromexico RewardsBooks Delta Air Lines
- Air France-KLM Flying BlueBooks Delta Air Lines
- China Eastern Eastern MilesBooks Delta Air Lines
- Delta SkyMilesBooks Delta Air Lines
- Garuda Indonesia GarudaMilesBooks Delta Air Lines
- Korean Air SKYPASSBooks Delta Air Lines
- SAS EuroBonusBooks Delta Air Lines
- Virgin Atlantic Flying ClubBooks Delta Air Lines
MSP to TYS with one stop
19 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Chicago (MDW)Delta Air Lines and Southwest Airlines, then Allegiant Air
- Via Chicago (ORD)American Airlines and United Airlines the whole way
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- Via Nashville (BNA)Southwest Airlines the whole way
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Memphis (MEM)Delta Air Lines, then Allegiant Air
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Bentonville (XNA)Delta Air Lines the whole way
- Via Dulles (IAD)United Airlines the whole way
- Via Washington (DCA)American Airlines and Delta Air Lines the whole way
- Via Baltimore (BWI)Southwest Airlines the whole way
- Via Fort Walton Beach (VPS)Sun Country Airlines and Delta Air Lines, then Allegiant Air
- Via Philadelphia (PHL)American Airlines the whole way
- Via Jacksonville (JAX)Delta Air Lines and Sun Country Airlines, then Allegiant Air
- Via New Orleans (MSY)Southwest Airlines the whole way
MSP to TYS: common questions
Which airlines fly nonstop from MSP to TYS?
Delta Air Lines (SkyTeam) flies nonstop from Minneapolis (MSP) to Knoxville (TYS).
How far is Minneapolis from Knoxville by plane?
Minneapolis (MSP) and Knoxville (TYS) are 792 miles (1,275 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book MSP to TYS award flights?
8 programs can book at least one of the nonstop airlines: Aeromexico Rewards, Air France-KLM Flying Blue, China Eastern Eastern Miles, Delta SkyMiles, Garuda Indonesia GarudaMiles, Korean Air SKYPASS, SAS EuroBonus and Virgin Atlantic Flying Club. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does MSP to TYS cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MSP to TYS with taxes and fees.
Where can I connect between Minneapolis and Knoxville?
The most direct connections are through Chicago (MDW), Chicago (ORD), Nashville (BNA), Detroit (DTW) and Memphis (MEM). On 15 of them the same airline flies both flights, for example American Airlines through Chicago.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.