Orlando (MCO) to Knoxville (TYS) flights
2 airlines fly nonstop from Orlando (MCO) to Knoxville (TYS): Allegiant Air and Southwest Airlines. The two airports are 533 miles (858 km) apart. There are also 16 ways to fly it with one stop, through Atlanta, Charlotte and Sarasota and more.
Airlines flying nonstop from MCO to TYS
- Allegiant AirNot in an alliance

- Southwest AirlinesNot in an allianceWho books it

MCO to TYS with one stop
16 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Atlanta (ATL)Delta Air Lines the whole way




- Via Charlotte (CLT)American Airlines the whole way



- Via Sarasota (SRQ)Southwest Airlines, then Allegiant Air


- Via Birmingham (BHM)Southwest Airlines, then United Airlines


- Via Nashville (BNA)Southwest Airlines the whole way




- Via Fort Lauderdale (FLL)Southwest Airlines and JetBlue Airways, then Allegiant Air



- Via Miami (MIA)American Airlines the whole way



- Via Memphis (MEM)Frontier Airlines and Southwest Airlines, then Allegiant Air



- Via Key West (EYW)Breeze Airways, then Allegiant Air


- Via New Orleans (MSY)Southwest Airlines the whole way





- Via Dulles (IAD)United Airlines the whole way




- Via Washington (DCA)American Airlines and Delta Air Lines the whole way

+1


- Via Baltimore (BWI)Southwest Airlines the whole way



- Via Detroit (DTW)Delta Air Lines the whole way




- Via Philadelphia (PHL)American Airlines the whole way





MCO to TYS: common questions
Which airlines fly nonstop from MCO to TYS?
Allegiant Air and Southwest Airlines fly nonstop from Orlando (MCO) to Knoxville (TYS).
How far is Orlando from Knoxville by plane?
Orlando (MCO) and Knoxville (TYS) are 533 miles (858 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does MCO to TYS cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MCO to TYS with taxes and fees.
Where can I connect between Orlando and Knoxville?
The most direct connections are through Atlanta (ATL), Charlotte (CLT), Sarasota (SRQ), Birmingham (BHM) and Nashville (BNA). On 10 of them the same airline flies both flights, for example Delta Air Lines through Atlanta.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.