Houston (HOU) to Knoxville (TYS) flights
One airline flies nonstop from Houston (HOU) to Knoxville (TYS): Allegiant Air. The two airports are 781 miles (1,257 km) apart. There are also 19 ways to fly it with one stop, through Birmingham, Nashville and Memphis and more.
Airlines flying nonstop from HOU to TYS
- Allegiant AirNot in an alliance

HOU to TYS with one stop
19 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Birmingham (BHM)Southwest Airlines, then United Airlines


- Via Nashville (BNA)Southwest Airlines the whole way


- Via Memphis (MEM)Southwest Airlines, then Allegiant Air


- Via New Orleans (MSY)Southwest Airlines the whole way



- Via Atlanta (ATL)Delta Air Lines the whole way



- Via Fort Walton Beach (VPS)Southwest Airlines, then Allegiant Air


- Via Dallas (DAL)Southwest Airlines the whole way


- Via Dallas (DFW)American Airlines the whole way


- Via Austin (AUS)Southwest Airlines the whole way


+1
- Via Charlotte (CLT)Southwest Airlines, then American Airlines


- Via Jacksonville (JAX)Southwest Airlines, then Allegiant Air


- Via Tampa (TPA)Southwest Airlines the whole way


- Via Sarasota (SRQ)Southwest Airlines, then Allegiant Air


- Via Orlando (MCO)Southwest Airlines the whole way



- Via Chicago (MDW)Southwest Airlines, then Allegiant Air


HOU to TYS: common questions
Which airlines fly nonstop from HOU to TYS?
Allegiant Air flies nonstop from Houston (HOU) to Knoxville (TYS).
How far is Houston from Knoxville by plane?
Houston (HOU) and Knoxville (TYS) are 781 miles (1,257 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does HOU to TYS cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for HOU to TYS with taxes and fees.
Where can I connect between Houston and Knoxville?
The most direct connections are through Birmingham (BHM), Nashville (BNA), Memphis (MEM), New Orleans (MSY) and Atlanta (ATL). On 9 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.