Des Moines (DSM) to Charlotte (CLT) flights
One airline flies nonstop from Des Moines (DSM) to Charlotte (CLT): American Airlines. The two airports are 814 miles (1,310 km) apart. American Airlines is in oneworld. There are also 15 ways to fly it with one stop, through Nashville, Chicago and Chicago and more.
Airlines flying nonstop from DSM to CLT
- American Airlinesoneworld · bookable with 9 programsWho books it

Book DSM to CLT with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Alaska Atmos RewardsBooks American Airlines
- American AAdvantageBooks American Airlines
- British Airways ClubBooks American Airlines
- Cathay Pacific Asia MilesBooks American Airlines
- Finnair PlusBooks American Airlines
- Iberia ClubBooks American Airlines
- JAL Mileage BankBooks American Airlines
- Qantas Frequent FlyerBooks American Airlines
- Qatar Airways Privilege ClubBooks American Airlines
DSM to CLT with one stop
15 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way




- Via Chicago (MDW)Southwest Airlines the whole way


- Via Chicago (ORD)American Airlines and United Airlines the whole way




- Via Atlanta (ATL)Delta Air Lines the whole way



- Via Detroit (DTW)Delta Air Lines the whole way



- Via Minneapolis (MSP)Delta Air Lines the whole way




- Via Washington (DCA)American Airlines the whole way


- Via Fort Walton Beach (VPS)Allegiant Air, then American Airlines


- Via Philadelphia (PHL)American Airlines the whole way




- Via New York (EWR)Allegiant Air, then American Airlines and United Airlines



- Via Dallas (DFW)American Airlines the whole way



- Via New York (LGA)Delta Air Lines and American Airlines the whole way





- Via Orlando (MCO)Frontier Airlines the whole way



- Via Sarasota (SRQ)Allegiant Air, then American Airlines


- Via Houston (IAH)United Airlines the whole way




DSM to CLT: common questions
Which airlines fly nonstop from DSM to CLT?
American Airlines (oneworld) flies nonstop from Des Moines (DSM) to Charlotte (CLT).
How far is Des Moines from Charlotte by plane?
Des Moines (DSM) and Charlotte (CLT) are 814 miles (1,310 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book DSM to CLT award flights?
9 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, American AAdvantage, British Airways Club, Cathay Pacific Asia Miles, Finnair Plus, Iberia Club, JAL Mileage Bank, Qantas Frequent Flyer and 1 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does DSM to CLT cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for DSM to CLT with taxes and fees.
Where can I connect between Des Moines and Charlotte?
The most direct connections are through Nashville (BNA), Chicago (MDW), Chicago (ORD), Atlanta (ATL) and Detroit (DTW). On 12 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.