United States · 814 miles (1,310 km)

Des Moines (DSM) to Charlotte (CLT) flights

One airline flies nonstop from Des Moines (DSM) to Charlotte (CLT): American Airlines. The two airports are 814 miles (1,310 km) apart. American Airlines is in oneworld. There are also 15 ways to fly it with one stop, through Nashville, Chicago and Chicago and more.

Airlines flying nonstop from DSM to CLT

  • American Airlines logo
    American Airlinesoneworld · bookable with 9 programsWho books it

Book DSM to CLT with points

Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.

DSM to CLT with one stop

15 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.

  • Via Nashville (BNA)Southwest Airlines the whole way
    Allegiant Air logo
    Southwest Airlines logo
    American Airlines logo
    Southwest Airlines logo
  • Via Chicago (MDW)Southwest Airlines the whole way
    Southwest Airlines logo
    Southwest Airlines logo
  • Via Chicago (ORD)American Airlines and United Airlines the whole way
    American Airlines logo
    United Airlines logo
    American Airlines logo
    United Airlines logo
  • Via Atlanta (ATL)Delta Air Lines the whole way
    Delta Air Lines logo
    American Airlines logo
    Delta Air Lines logo
  • Via Detroit (DTW)Delta Air Lines the whole way
    Delta Air Lines logo
    American Airlines logo
    Delta Air Lines logo
  • Via Minneapolis (MSP)Delta Air Lines the whole way
    Delta Air Lines logo
    American Airlines logo
    Delta Air Lines logo
    Sun Country Airlines logo
  • Via Washington (DCA)American Airlines the whole way
    American Airlines logo
    American Airlines logo
  • Via Fort Walton Beach (VPS)Allegiant Air, then American Airlines
    Allegiant Air logo
    American Airlines logo
  • Via Philadelphia (PHL)American Airlines the whole way
    American Airlines logo
    Allegiant Air logo
    American Airlines logo
    Frontier Airlines logo
  • Via New York (EWR)Allegiant Air, then American Airlines and United Airlines
    Allegiant Air logo
    American Airlines logo
    United Airlines logo
  • Via Dallas (DFW)American Airlines the whole way
    American Airlines logo
    American Airlines logo
    Frontier Airlines logo
  • Via New York (LGA)Delta Air Lines and American Airlines the whole way
    Delta Air Lines logo
    American Airlines logo
    American Airlines logo
    Delta Air Lines logo
    Frontier Airlines logo
  • Via Orlando (MCO)Frontier Airlines the whole way
    Frontier Airlines logo
    American Airlines logo
    Frontier Airlines logo
  • Via Sarasota (SRQ)Allegiant Air, then American Airlines
    Allegiant Air logo
    American Airlines logo
  • Via Houston (IAH)United Airlines the whole way
    United Airlines logo
    American Airlines logo
    United Airlines logo
    Frontier Airlines logo

DSM to CLT: common questions

Which airlines fly nonstop from DSM to CLT?

American Airlines (oneworld) flies nonstop from Des Moines (DSM) to Charlotte (CLT).

How far is Des Moines from Charlotte by plane?

Des Moines (DSM) and Charlotte (CLT) are 814 miles (1,310 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.

Which points programs can book DSM to CLT award flights?

9 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, American AAdvantage, British Airways Club, Cathay Pacific Asia Miles, Finnair Plus, Iberia Club, JAL Mileage Bank, Qantas Frequent Flyer and 1 more. Which flights each can book depends on its partners, so check the airline before you transfer points.

How many miles does DSM to CLT cost?

It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for DSM to CLT with taxes and fees.

Where can I connect between Des Moines and Charlotte?

The most direct connections are through Nashville (BNA), Chicago (MDW), Chicago (ORD), Atlanta (ATL) and Detroit (DTW). On 12 of them the same airline flies both flights, for example Southwest Airlines through Nashville.

More routes

Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.