Charlotte (CLT) to Des Moines (DSM) flights
One airline flies nonstop from Charlotte (CLT) to Des Moines (DSM): American Airlines. The two airports are 814 miles (1,310 km) apart. American Airlines is in oneworld. There are also 15 ways to fly it with one stop, through Nashville, Chicago and Chicago and more.
Airlines flying nonstop from CLT to DSM
- American Airlinesoneworld · bookable with 9 programsWho books it

Book CLT to DSM with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Alaska Atmos RewardsBooks American Airlines
- American AAdvantageBooks American Airlines
- British Airways ClubBooks American Airlines
- Cathay Pacific Asia MilesBooks American Airlines
- Finnair PlusBooks American Airlines
- Iberia ClubBooks American Airlines
- JAL Mileage BankBooks American Airlines
- Qantas Frequent FlyerBooks American Airlines
- Qatar Airways Privilege ClubBooks American Airlines
CLT to DSM with one stop
15 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way




- Via Chicago (MDW)Southwest Airlines the whole way


- Via Chicago (ORD)American Airlines and United Airlines the whole way




- Via Atlanta (ATL)Delta Air Lines the whole way



- Via Detroit (DTW)Delta Air Lines the whole way



- Via Minneapolis (MSP)Delta Air Lines the whole way




- Via Washington (DCA)American Airlines the whole way


- Via Fort Walton Beach (VPS)American Airlines, then Allegiant Air


- Via Philadelphia (PHL)American Airlines the whole way




- Via New York (EWR)American Airlines and United Airlines, then Allegiant Air



- Via Dallas (DFW)American Airlines the whole way



- Via New York (LGA)American Airlines and Delta Air Lines the whole way





- Via Orlando (MCO)Frontier Airlines the whole way



- Via Sarasota (SRQ)American Airlines, then Allegiant Air


- Via Houston (IAH)United Airlines the whole way




CLT to DSM: common questions
Which airlines fly nonstop from CLT to DSM?
American Airlines (oneworld) flies nonstop from Charlotte (CLT) to Des Moines (DSM).
How far is Charlotte from Des Moines by plane?
Charlotte (CLT) and Des Moines (DSM) are 814 miles (1,310 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book CLT to DSM award flights?
9 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, American AAdvantage, British Airways Club, Cathay Pacific Asia Miles, Finnair Plus, Iberia Club, JAL Mileage Bank, Qantas Frequent Flyer and 1 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does CLT to DSM cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for CLT to DSM with taxes and fees.
Where can I connect between Charlotte and Des Moines?
The most direct connections are through Nashville (BNA), Chicago (MDW), Chicago (ORD), Atlanta (ATL) and Detroit (DTW). On 12 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.