Quito (UIO) to Santiago (SCL) flights
One airline flies nonstop from Quito (UIO) to Santiago (SCL): LATAM Airlines. The two airports are 2,351 miles (3,783 km) apart. There are also 6 ways to fly it with one stop, through Lima, Guayaquil and Bogota and more.
Airlines flying nonstop from UIO to SCL
- LATAM AirlinesNot in an alliance · bookable with 3 programsWho books it
Book UIO to SCL with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Alaska Atmos RewardsBooks LATAM Airlines
- Delta SkyMilesBooks LATAM Airlines
- Virgin Atlantic Flying ClubBooks LATAM Airlines
UIO to SCL with one stop
6 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Lima (LIM)LATAM Airlines and JetSMART the whole way
- Via Guayaquil (GYE)LATAM Airlines the whole way
- Via Bogota (BOG)AVIANCA and LATAM Airlines the whole way
- Via Medellin (MDE)AVIANCA, then JetSMART
- Via Buenos Aires (EZE)AVIANCA, then Sky Airline, KLM and 1 more
- Via Panama City (PTY)Copa Airlines the whole way
UIO to SCL: common questions
Which airlines fly nonstop from UIO to SCL?
LATAM Airlines flies nonstop from Quito (UIO) to Santiago (SCL).
How far is Quito from Santiago by plane?
Quito (UIO) and Santiago (SCL) are 2,351 miles (3,783 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book UIO to SCL award flights?
3 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, Delta SkyMiles and Virgin Atlantic Flying Club. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does UIO to SCL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for UIO to SCL with taxes and fees.
Where can I connect between Quito and Santiago?
The most direct connections are through Lima (LIM), Guayaquil (GYE), Bogota (BOG), Medellin (MDE) and Buenos Aires (EZE). On 4 of them the same airline flies both flights, for example LATAM Airlines through Lima.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.