Santander (SDR) to Brussels (CRL) flights
One airline flies nonstop from Santander (SDR) to Brussels (CRL): Ryanair. The two airports are 623 miles (1,002 km) apart. There are also 14 ways to fly it with one stop, through Barcelona, Madrid and Manchester and more.
Airlines flying nonstop from SDR to CRL
- RyanairNot in an alliance

SDR to CRL with one stop
14 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Barcelona (BCN)Vueling, then Ryanair


- Via Madrid (MAD)Iberia and Volotea, then Ryanair



- Via Manchester (MAN)Ryanair and Ryanair UK the whole way




- Via Valencia (VLC)Volotea, then Ryanair


- Via Palma de Mallorca (PMI)Vueling, then Ryanair


- Via Dublin (DUB)Ryanair the whole way


- Via Menorca (MAH)Volotea, then Ryanair


- Via Ibiza (IBZ)Vueling, then Ryanair


- Via Alicante (ALC)Vueling, then Ryanair


- Via Bologna (BLQ)Ryanair the whole way


- Via Venice (TSF)Ryanair the whole way


- Via Edinburgh (EDI)Ryanair and Ryanair UK the whole way




- Via Sevilla (SVQ)Volotea, then Ryanair


- Via Malaga (AGP)Volotea, then Ryanair


SDR to CRL: common questions
Which airlines fly nonstop from SDR to CRL?
Ryanair flies nonstop from Santander (SDR) to Brussels (CRL).
How far is Santander from Brussels by plane?
Santander (SDR) and Brussels (CRL) are 623 miles (1,002 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does SDR to CRL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for SDR to CRL with taxes and fees.
Where can I connect between Santander and Brussels?
The most direct connections are through Barcelona (BCN), Madrid (MAD), Manchester (MAN), Valencia (VLC) and Palma de Mallorca (PMI). On 5 of them the same airline flies both flights, for example Ryanair through Manchester.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.