Fort Myers (RSW) to Des Moines (DSM) flights
One airline flies nonstop from Fort Myers (RSW) to Des Moines (DSM): Allegiant Air. The two airports are 1,238 miles (1,992 km) apart. There are also 17 ways to fly it with one stop, through Nashville, Atlanta and Orlando and more.
Airlines flying nonstop from RSW to DSM
- Allegiant AirNot in an alliance

RSW to DSM with one stop
17 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way



- Via Atlanta (ATL)Delta Air Lines the whole way


- Via Orlando (MCO)Southwest Airlines, then Frontier Airlines


- Via Chicago (MDW)Southwest Airlines the whole way


- Via Charlotte (CLT)American Airlines the whole way


- Via Chicago (ORD)American Airlines and United Airlines the whole way





- Via Detroit (DTW)Delta Air Lines the whole way



- Via Dallas (DFW)American Airlines the whole way


- Via Minneapolis (MSP)Delta Air Lines the whole way




- Via Houston (IAH)United Airlines the whole way


- Via Washington (DCA)American Airlines the whole way


- Via Austin (AUS)Southwest Airlines and Delta Air Lines, then Allegiant Air



- Via Philadelphia (PHL)American Airlines the whole way




- Via New York (EWR)United Airlines, then Allegiant Air


- Via New York (LGA)Delta Air Lines and American Airlines the whole way




RSW to DSM: common questions
Which airlines fly nonstop from RSW to DSM?
Allegiant Air flies nonstop from Fort Myers (RSW) to Des Moines (DSM).
How far is Fort Myers from Des Moines by plane?
Fort Myers (RSW) and Des Moines (DSM) are 1,238 miles (1,992 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does RSW to DSM cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for RSW to DSM with taxes and fees.
Where can I connect between Fort Myers and Des Moines?
The most direct connections are through Nashville (BNA), Atlanta (ATL), Orlando (MCO), Chicago (MDW) and Charlotte (CLT). On 13 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.