Raleigh/Durham (RDU) to Saint Louis (STL) flights
One airline flies nonstop from Raleigh/Durham (RDU) to Saint Louis (STL): Southwest Airlines. The two airports are 667 miles (1,073 km) apart. There are also 25 ways to fly it with one stop, through Charlotte, Nashville and Columbus and more.
Airlines flying nonstop from RDU to STL
- Southwest AirlinesNot in an allianceWho books it
RDU to STL with one stop
25 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Charlotte (CLT)American Airlines the whole way
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Columbus (CMH)Breeze Airways, then Southwest Airlines
- Via Atlanta (ATL)Delta Air Lines and Frontier Airlines the whole way
- Via Pittsburgh (PIT)American Airlines and Breeze Airways, then Southwest Airlines
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Cleveland (CLE)Frontier Airlines, then Southwest Airlines
- Via Dulles (IAD)United Airlines the whole way
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Baltimore (BWI)Southwest Airlines the whole way
- Via Kansas City (MCI)Southwest Airlines the whole way
- Via Philadelphia (PHL)American Airlines the whole way
- Via Jacksonville (JAX)Breeze Airways, then Southwest Airlines
RDU to STL: common questions
Which airlines fly nonstop from RDU to STL?
Southwest Airlines flies nonstop from Raleigh/Durham (RDU) to Saint Louis (STL).
How far is Raleigh/Durham from Saint Louis by plane?
Raleigh/Durham (RDU) and Saint Louis (STL) are 667 miles (1,073 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does RDU to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for RDU to STL with taxes and fees.
Where can I connect between Raleigh/Durham and Saint Louis?
The most direct connections are through Charlotte (CLT), Nashville (BNA), Columbus (CMH), Atlanta (ATL) and Pittsburgh (PIT). On 19 of them the same airline flies both flights, for example American Airlines through Charlotte.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.