Panama City (PTY) to San Francisco (SFO) flights
One airline flies nonstop from Panama City (PTY) to San Francisco (SFO): Copa Airlines. The two airports are 3,321 miles (5,345 km) apart. Copa Airlines is in Star Alliance. There are also 30 ways to fly it with one stop, through Monterrey, Belize City and Las Vegas and more.
Airlines flying nonstop from PTY to SFO
- Copa AirlinesStar Alliance · bookable with 13 programsWho books it

Book PTY to SFO with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Air Canada AeroplanBooks Copa Airlines
- Air France-KLM Flying BlueBooks Copa Airlines
- Air New Zealand AirpointsBooks Copa Airlines
- ANA Mileage ClubBooks Copa Airlines
- Avianca LifeMilesBooks Copa Airlines
- Emirates SkywardsBooks Copa Airlines
- EVA Air Infinity MileageLandsBooks Copa Airlines
- Lufthansa Miles & MoreBooks Copa Airlines
- Singapore Airlines KrisFlyerBooks Copa Airlines
- TAP Miles&GoBooks Copa Airlines
- Thai Royal Orchid PlusBooks Copa Airlines
- Turkish Airlines Miles&SmilesBooks Copa Airlines
- United MileagePlusBooks Copa Airlines
PTY to SFO with one stop
30 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Monterrey (MTY)Copa Airlines, then United Airlines


- Via Belize City (BZE)Copa Airlines, then United Airlines


- Via Las Vegas (LAS)Copa Airlines, then Alaska Airlines, Frontier Airlines and 2 more


+1
- Via Los Angeles (LAX)Copa Airlines, then American Airlines, Alaska Airlines and 4 more


+3
- Via San Diego (SAN)Copa Airlines, then Alaska Airlines, United Airlines and 2 more


+1
- Via Guatemala City (GUA)Copa Airlines, then AVIANCA


- Via San Salvador (SAL)AVIANCA the whole way



- Via Cancun (CUN)Copa Airlines, then United Airlines and Alaska Airlines



- Via San Jose (SJO)AVIANCA and Copa Airlines, then United Airlines



- Via Austin (AUS)Copa Airlines, then United Airlines, Southwest Airlines and 1 more




- Via Mexico City (MEX)Aeromexico the whole way




- Via Houston (IAH)United Airlines the whole way


- Via Guadalajara (GDL)Copa Airlines, then Aeromexico


- Via San Jose Cabo (SJD)Copa Airlines, then Alaska Airlines and United Airlines



- Via Denver (DEN)Copa Airlines, then Frontier Airlines, United Airlines and 1 more




PTY to SFO: common questions
Which airlines fly nonstop from PTY to SFO?
Copa Airlines (Star Alliance) flies nonstop from Panama City (PTY) to San Francisco (SFO).
How far is Panama City from San Francisco by plane?
Panama City (PTY) and San Francisco (SFO) are 3,321 miles (5,345 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book PTY to SFO award flights?
13 programs can book at least one of the nonstop airlines: Air Canada Aeroplan, Air France-KLM Flying Blue, Air New Zealand Airpoints, ANA Mileage Club, Avianca LifeMiles, Emirates Skywards, EVA Air Infinity MileageLands, Lufthansa Miles & More and 5 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does PTY to SFO cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for PTY to SFO with taxes and fees.
Where can I connect between Panama City and San Francisco?
The most direct connections are through Monterrey (MTY), Belize City (BZE), Las Vegas (LAS), Los Angeles (LAX) and San Diego (SAN). On 7 of them the same airline flies both flights, for example AVIANCA through San Salvador.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.