Panama City (PTY) to Mexico City (MEX) flights
2 airlines fly nonstop from Panama City (PTY) to Mexico City (MEX): Aeromexico and Copa Airlines. The two airports are 1,498 miles (2,411 km) apart. Aeromexico is in SkyTeam and Copa Airlines is in Star Alliance. There are also 23 ways to fly it with one stop, through Guatemala City, Comayagua and Managua and more.
Airlines flying nonstop from PTY to MEX
- AeromexicoSkyTeam Β· bookable with 8 programsWho books it

- Copa AirlinesStar Alliance Β· bookable with 13 programsWho books it

Book PTY to MEX with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Air France-KLM Flying BlueBooks Aeromexico, Copa Airlines
- Aeromexico RewardsBooks Aeromexico
- Air Canada AeroplanBooks Copa Airlines
- Air New Zealand AirpointsBooks Copa Airlines
- ANA Mileage ClubBooks Copa Airlines
- Avianca LifeMilesBooks Copa Airlines
- China Eastern Eastern MilesBooks Aeromexico
- Delta SkyMilesBooks Aeromexico
- Emirates SkywardsBooks Copa Airlines
- EVA Air Infinity MileageLandsBooks Copa Airlines
- Garuda Indonesia GarudaMilesBooks Aeromexico
- Korean Air SKYPASSBooks Aeromexico
- Lufthansa Miles & MoreBooks Copa Airlines
- SAS EuroBonusBooks Aeromexico
- Singapore Airlines KrisFlyerBooks Copa Airlines
- TAP Miles&GoBooks Copa Airlines
- Thai Royal Orchid PlusBooks Copa Airlines
- Turkish Airlines Miles&SmilesBooks Copa Airlines
- United MileagePlusBooks Copa Airlines
- Virgin Atlantic Flying ClubBooks Aeromexico
PTY to MEX with one stop
23 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Guatemala City (GUA)Copa Airlines, then Aeromexico, Volaris Costa Rica and 1 more

Q6
- Via Comayagua (XPL)Copa Airlines, then Aeromexico


- Via Managua (MGA)Copa Airlines, then Aeromexico


- Via San Salvador (SAL)AVIANCA the whole way



N3 - Via San Pedro Sula (SAP)Copa Airlines, then Aeromexico


- Via San Jose (SJO)AVIANCA the whole way



Q6 - Via Cancun (CUN)Copa Airlines, then Aeromexico, VivaAerobus and 1 more




- Via Cartagena (CTG)Copa Airlines, then Aeromexico


- Via Guadalajara (GDL)Copa Airlines, then Aeromexico, VivaAerobus and 1 more




- Via Havana (HAV)Copa Airlines, then Aeromexico


- Via Medellin (MDE)Copa Airlines, then Aeromexico and AVIANCA



- Via Monterrey (MTY)Copa Airlines, then Aeromexico, VivaAerobus and 1 more




- Via Cali (CLO)Copa Airlines, then Aeromexico


- Via Miami (MIA)American Airlines the whole way





- Via Bogota (BOG)AVIANCA the whole way




PTY to MEX: common questions
Which airlines fly nonstop from PTY to MEX?
Aeromexico (SkyTeam) and Copa Airlines (Star Alliance) fly nonstop from Panama City (PTY) to Mexico City (MEX).
How far is Panama City from Mexico City by plane?
Panama City (PTY) and Mexico City (MEX) are 1,498 miles (2,411 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book PTY to MEX award flights?
20 programs can book at least one of the nonstop airlines: Air France-KLM Flying Blue, Aeromexico Rewards, Air Canada Aeroplan, Air New Zealand Airpoints, ANA Mileage Club, Avianca LifeMiles, China Eastern Eastern Miles, Delta SkyMiles and 12 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does PTY to MEX cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for PTY to MEX with taxes and fees.
Where can I connect between Panama City and Mexico City?
The most direct connections are through Guatemala City (GUA), Comayagua (XPL), Managua (MGA), San Salvador (SAL) and San Pedro Sula (SAP). On 5 of them the same airline flies both flights, for example AVIANCA through San Salvador.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.