Pisa (PSA) to Brussels (BRU) flights
One airline flies nonstop from Pisa (PSA) to Brussels (BRU): Ryanair. The two airports are 569 miles (916 km) apart. There are also 26 ways to fly it with one stop, through Milan, Frankfurt and Amsterdam and more.
Airlines flying nonstop from PSA to BRU
- RyanairNot in an alliance

PSA to BRU with one stop
26 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Milan (MXP)Neos, then Brussels AirlinesNO

- Via Frankfurt (FRA)Air Dolomiti, then Lufthansa and Brussels Airlines



- Via Amsterdam (AMS)Transavia, then KLM


- Via Prague (PRG)Ryanair, then Brussels Airlines and SmartWings



- Via Olbia (OLB)Volotea, then Brussels Airlines


- Via Zadar (ZAD)Ryanair, then Brussels Airlines


- Via London (LHR)British Airways the whole way



- Via Toulouse (TLS)Volotea, then Brussels Airlines


- Via Nantes (NTE)Volotea, then easyJet


- Via Berlin (BER)easyJet and Ryanair, then Brussels Airlines



- Via Girona (GRO)Ryanair the whole way
TB
- Via Budapest (BUD)Ryanair, then Brussels Airlines


- Via Manchester (MAN)Jet2, easyJet and 1 more, then Brussels Airlines




- Via Bari (BRI)Ryanair, then Transavia


- Via Palma de Mallorca (PMI)Ryanair the whole way


TB+1
PSA to BRU: common questions
Which airlines fly nonstop from PSA to BRU?
Ryanair flies nonstop from Pisa (PSA) to Brussels (BRU).
How far is Pisa from Brussels by plane?
Pisa (PSA) and Brussels (BRU) are 569 miles (916 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does PSA to BRU cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for PSA to BRU with taxes and fees.
Where can I connect between Pisa and Brussels?
The most direct connections are through Milan (MXP), Frankfurt (FRA), Amsterdam (AMS), Prague (PRG) and Olbia (OLB). On 6 of them the same airline flies both flights, for example British Airways through London.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.