Italy to Belgium · 569 miles (916 km)

Pisa (PSA) to Brussels (BRU) flights

One airline flies nonstop from Pisa (PSA) to Brussels (BRU): Ryanair. The two airports are 569 miles (916 km) apart. There are also 26 ways to fly it with one stop, through Milan, Frankfurt and Amsterdam and more.

Airlines flying nonstop from PSA to BRU

  • Ryanair logo
    RyanairNot in an alliance

PSA to BRU with one stop

26 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.

  • Via Milan (MXP)Neos, then Brussels Airlines
    NO
    Brussels Airlines logo
  • Via Frankfurt (FRA)Air Dolomiti, then Lufthansa and Brussels Airlines
    Air Dolomiti logo
    Lufthansa logo
    Brussels Airlines logo
  • Via Amsterdam (AMS)Transavia, then KLM
    Transavia logo
    KLM logo
  • Via Prague (PRG)Ryanair, then Brussels Airlines and SmartWings
    Ryanair logo
    Brussels Airlines logo
    SmartWings logo
  • Via Olbia (OLB)Volotea, then Brussels Airlines
    Volotea logo
    Brussels Airlines logo
  • Via Zadar (ZAD)Ryanair, then Brussels Airlines
    Ryanair logo
    Brussels Airlines logo
  • Via London (LHR)British Airways the whole way
    British Airways logo
    British Airways logo
    Brussels Airlines logo
  • Via Toulouse (TLS)Volotea, then Brussels Airlines
    Volotea logo
    Brussels Airlines logo
  • Via Nantes (NTE)Volotea, then easyJet
    Volotea logo
    easyJet logo
  • Via Berlin (BER)easyJet and Ryanair, then Brussels Airlines
    easyJet logo
    Ryanair logo
    Brussels Airlines logo
  • Via Girona (GRO)Ryanair the whole way
    Ryanair logo
    TB
    Ryanair logo
  • Via Budapest (BUD)Ryanair, then Brussels Airlines
    Ryanair logo
    Brussels Airlines logo
  • Via Manchester (MAN)Jet2, easyJet and 1 more, then Brussels Airlines
    Jet2 logo
    easyJet logo
    Ryanair logo
    Brussels Airlines logo
  • Via Bari (BRI)Ryanair, then Transavia
    Ryanair logo
    Transavia logo
  • Via Palma de Mallorca (PMI)Ryanair the whole way
    Ryanair logo
    Ryanair logo
    Brussels Airlines logo
    TB
    +1
See all 26 in Routes

PSA to BRU: common questions

Which airlines fly nonstop from PSA to BRU?

Ryanair flies nonstop from Pisa (PSA) to Brussels (BRU).

How far is Pisa from Brussels by plane?

Pisa (PSA) and Brussels (BRU) are 569 miles (916 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.

How many miles does PSA to BRU cost?

It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for PSA to BRU with taxes and fees.

Where can I connect between Pisa and Brussels?

The most direct connections are through Milan (MXP), Frankfurt (FRA), Amsterdam (AMS), Prague (PRG) and Olbia (OLB). On 6 of them the same airline flies both flights, for example British Airways through London.

More routes

Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.