Chicago (ORD) to Greenville (GSP) flights
2 airlines fly nonstop from Chicago (ORD) to Greenville (GSP): American Airlines and United Airlines. The two airports are 578 miles (930 km) apart. American Airlines is in oneworld and United Airlines is in Star Alliance. There are also 17 ways to fly it with one stop, through Cincinnati, Columbus and Nashville and more.
Airlines flying nonstop from ORD to GSP
- American Airlinesoneworld · bookable with 9 programsWho books it

- United AirlinesStar Alliance · bookable with 13 programsWho books it

Book ORD to GSP with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Air Canada AeroplanBooks United Airlines
- Air New Zealand AirpointsBooks United Airlines
- Alaska Atmos RewardsBooks American Airlines
- American AAdvantageBooks American Airlines
- ANA Mileage ClubBooks United Airlines
- Avianca LifeMilesBooks United Airlines
- British Airways ClubBooks American Airlines
- Cathay Pacific Asia MilesBooks American Airlines
- Emirates SkywardsBooks United Airlines
- EVA Air Infinity MileageLandsBooks United Airlines
- Finnair PlusBooks American Airlines
- Iberia ClubBooks American Airlines
- JAL Mileage BankBooks American Airlines
- JetBlue TrueBlueBooks United Airlines
- Lufthansa Miles & MoreBooks United Airlines
- Qantas Frequent FlyerBooks American Airlines
- Qatar Airways Privilege ClubBooks American Airlines
- Singapore Airlines KrisFlyerBooks United Airlines
- TAP Miles&GoBooks United Airlines
- Thai Royal Orchid PlusBooks United Airlines
- Turkish Airlines Miles&SmilesBooks United Airlines
- United MileagePlusBooks United Airlines
ORD to GSP with one stop
17 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Cincinnati (CVG)American Airlines and United Airlines, then Breeze Airways



- Via Columbus (CMH)American Airlines and United Airlines, then Breeze Airways



- Via Nashville (BNA)American Airlines and United Airlines, then Southwest Airlines



- Via Charlotte (CLT)American Airlines the whole way



- Via Detroit (DTW)Delta Air Lines the whole way




- Via Atlanta (ATL)Delta Air Lines the whole way

+1

- Via Pittsburgh (PIT)American Airlines and United Airlines, then Breeze Airways



- Via Dulles (IAD)United Airlines the whole way


- Via Washington (DCA)American Airlines the whole way



- Via Baltimore (BWI)American Airlines, United Airlines and 1 more, then Southwest Airlines




- Via Philadelphia (PHL)American Airlines the whole way




- Via New York (EWR)United Airlines the whole way



- Via New York (LGA)American Airlines and Delta Air Lines the whole way





- Via New Haven (HVN)Avelo Airlines the whole way


- Via Orlando (MCO)American Airlines, Frontier Airlines and 1 more, then Breeze Airways




ORD to GSP: common questions
Which airlines fly nonstop from ORD to GSP?
American Airlines (oneworld) and United Airlines (Star Alliance) fly nonstop from Chicago (ORD) to Greenville (GSP).
How far is Chicago from Greenville by plane?
Chicago (ORD) and Greenville (GSP) are 578 miles (930 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book ORD to GSP award flights?
22 programs can book at least one of the nonstop airlines: Air Canada Aeroplan, Air New Zealand Airpoints, Alaska Atmos Rewards, American AAdvantage, ANA Mileage Club, Avianca LifeMiles, British Airways Club, Cathay Pacific Asia Miles and 14 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does ORD to GSP cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for ORD to GSP with taxes and fees.
Where can I connect between Chicago and Greenville?
The most direct connections are through Cincinnati (CVG), Columbus (CMH), Nashville (BNA), Charlotte (CLT) and Detroit (DTW). On 9 of them the same airline flies both flights, for example American Airlines through Charlotte.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.