United States · 578 miles (930 km)

Chicago (ORD) to Greenville (GSP) flights

2 airlines fly nonstop from Chicago (ORD) to Greenville (GSP): American Airlines and United Airlines. The two airports are 578 miles (930 km) apart. American Airlines is in oneworld and United Airlines is in Star Alliance. There are also 17 ways to fly it with one stop, through Cincinnati, Columbus and Nashville and more.

Airlines flying nonstop from ORD to GSP

  • American Airlines logo
    American Airlinesoneworld · bookable with 9 programsWho books it
  • United Airlines logo
    United AirlinesStar Alliance · bookable with 13 programsWho books it

Book ORD to GSP with points

Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.

ORD to GSP with one stop

17 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.

  • Via Cincinnati (CVG)American Airlines and United Airlines, then Breeze Airways
    American Airlines logo
    United Airlines logo
    Breeze Airways logo
  • Via Columbus (CMH)American Airlines and United Airlines, then Breeze Airways
    American Airlines logo
    United Airlines logo
    Breeze Airways logo
  • Via Nashville (BNA)American Airlines and United Airlines, then Southwest Airlines
    American Airlines logo
    United Airlines logo
    Southwest Airlines logo
  • Via Charlotte (CLT)American Airlines the whole way
    American Airlines logo
    United Airlines logo
    American Airlines logo
  • Via Detroit (DTW)Delta Air Lines the whole way
    American Airlines logo
    Delta Air Lines logo
    United Airlines logo
    Delta Air Lines logo
  • Via Atlanta (ATL)Delta Air Lines the whole way
    American Airlines logo
    Delta Air Lines logo
    United Airlines logo
    +1
    Delta Air Lines logo
  • Via Pittsburgh (PIT)American Airlines and United Airlines, then Breeze Airways
    American Airlines logo
    United Airlines logo
    Breeze Airways logo
  • Via Dulles (IAD)United Airlines the whole way
    United Airlines logo
    United Airlines logo
  • Via Washington (DCA)American Airlines the whole way
    American Airlines logo
    United Airlines logo
    American Airlines logo
  • Via Baltimore (BWI)American Airlines, United Airlines and 1 more, then Southwest Airlines
    American Airlines logo
    United Airlines logo
    Frontier Airlines logo
    Southwest Airlines logo
  • Via Philadelphia (PHL)American Airlines the whole way
    American Airlines logo
    United Airlines logo
    Frontier Airlines logo
    American Airlines logo
  • Via New York (EWR)United Airlines the whole way
    American Airlines logo
    United Airlines logo
    United Airlines logo
  • Via New York (LGA)American Airlines and Delta Air Lines the whole way
    American Airlines logo
    Delta Air Lines logo
    United Airlines logo
    Delta Air Lines logo
    American Airlines logo
  • Via New Haven (HVN)Avelo Airlines the whole way
    Avelo Airlines logo
    Avelo Airlines logo
  • Via Orlando (MCO)American Airlines, Frontier Airlines and 1 more, then Breeze Airways
    American Airlines logo
    Frontier Airlines logo
    United Airlines logo
    Breeze Airways logo
See all 17 in Routes

ORD to GSP: common questions

Which airlines fly nonstop from ORD to GSP?

American Airlines (oneworld) and United Airlines (Star Alliance) fly nonstop from Chicago (ORD) to Greenville (GSP).

How far is Chicago from Greenville by plane?

Chicago (ORD) and Greenville (GSP) are 578 miles (930 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.

Which points programs can book ORD to GSP award flights?

22 programs can book at least one of the nonstop airlines: Air Canada Aeroplan, Air New Zealand Airpoints, Alaska Atmos Rewards, American AAdvantage, ANA Mileage Club, Avianca LifeMiles, British Airways Club, Cathay Pacific Asia Miles and 14 more. Which flights each can book depends on its partners, so check the airline before you transfer points.

How many miles does ORD to GSP cost?

It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for ORD to GSP with taxes and fees.

Where can I connect between Chicago and Greenville?

The most direct connections are through Cincinnati (CVG), Columbus (CMH), Nashville (BNA), Charlotte (CLT) and Detroit (DTW). On 9 of them the same airline flies both flights, for example American Airlines through Charlotte.

More routes

Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.