Myrtle Beach (MYR) to Chicago (MDW) flights
One airline flies nonstop from Myrtle Beach (MYR) to Chicago (MDW): Southwest Airlines. The two airports are 738 miles (1,188 km) apart. There are also 20 ways to fly it with one stop, through Cincinnati, Charlotte and Detroit and more.
Airlines flying nonstop from MYR to MDW
- Southwest AirlinesNot in an allianceWho books it

MYR to MDW with one stop
20 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Cincinnati (CVG)Allegiant Air, then Southwest Airlines


- Via Charlotte (CLT)American Airlines, then Southwest Airlines


- Via Detroit (DTW)Delta Air Lines the whole way



- Via Nashville (BNA)Southwest Airlines the whole way


- Via Pittsburgh (PIT)Southwest Airlines the whole way




- Via Atlanta (ATL)Delta Air Lines the whole way




- Via Washington (DCA)American Airlines, then Southwest Airlines


- Via Saint Louis (STL)Southwest Airlines the whole way


- Via Baltimore (BWI)Southwest Airlines the whole way


- Via Philadelphia (PHL)American Airlines and Frontier Airlines, then Southwest Airlines



- Via Rochester (ROC)Breeze Airways, then Southwest Airlines


- Via New York (LGA)American Airlines and Delta Air Lines, then Southwest Airlines



- Via Orlando (MCO)Breeze Airways, then Southwest Airlines and Frontier Airlines



- Via Albany (ALB)Allegiant Air, then Southwest Airlines


- Via Minneapolis (MSP)Delta Air Lines the whole way




MYR to MDW: common questions
Which airlines fly nonstop from MYR to MDW?
Southwest Airlines flies nonstop from Myrtle Beach (MYR) to Chicago (MDW).
How far is Myrtle Beach from Chicago by plane?
Myrtle Beach (MYR) and Chicago (MDW) are 738 miles (1,188 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does MYR to MDW cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MYR to MDW with taxes and fees.
Where can I connect between Myrtle Beach and Chicago?
The most direct connections are through Cincinnati (CVG), Charlotte (CLT), Detroit (DTW), Nashville (BNA) and Pittsburgh (PIT). On 7 of them the same airline flies both flights, for example Delta Air Lines through Detroit.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.