New Orleans (MSY) to Louisville (SDF) flights
2 airlines fly nonstop from New Orleans (MSY) to Louisville (SDF): Breeze Airways and Southwest Airlines. The two airports are 622 miles (1,001 km) apart. There are also 19 ways to fly it with one stop, through Nashville, Atlanta and Charlotte and more.
Airlines flying nonstop from MSY to SDF
- Breeze AirwaysNot in an alliance
- Southwest AirlinesNot in an allianceWho books it
MSY to SDF with one stop
19 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Houston (IAH)United Airlines the whole way
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Houston (HOU)Southwest Airlines the whole way
- Via Charleston (CHS)Breeze Airways the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Dallas (DAL)Southwest Airlines the whole way
- Via Dallas (DFW)American Airlines the whole way
- Via Raleigh/Durham (RDU)Breeze Airways the whole way
- Via Tampa (TPA)Southwest Airlines and Breeze Airways the whole way
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Pittsburgh (PIT)Breeze Airways the whole way
- Via Orlando (MCO)Southwest Airlines the whole way
MSY to SDF: common questions
Which airlines fly nonstop from MSY to SDF?
Breeze Airways and Southwest Airlines fly nonstop from New Orleans (MSY) to Louisville (SDF).
How far is New Orleans from Louisville by plane?
New Orleans (MSY) and Louisville (SDF) are 622 miles (1,001 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does MSY to SDF cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MSY to SDF with taxes and fees.
Where can I connect between New Orleans and Louisville?
The most direct connections are through Nashville (BNA), Atlanta (ATL), Charlotte (CLT), Houston (IAH) and Chicago (MDW). On 19 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.