New Orleans (MSY) to Lexington (LEX) flights
One airline flies nonstop from New Orleans (MSY) to Lexington (LEX): American Airlines. The two airports are 644 miles (1,036 km) apart. American Airlines is in oneworld. There are also 9 ways to fly it with one stop, through Atlanta, Charlotte and Chicago and more.
Airlines flying nonstop from MSY to LEX
- American Airlinesoneworld · bookable with 9 programsWho books it

Book MSY to LEX with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Alaska Atmos RewardsBooks American Airlines
- American AAdvantageBooks American Airlines
- British Airways ClubBooks American Airlines
- Cathay Pacific Asia MilesBooks American Airlines
- Finnair PlusBooks American Airlines
- Iberia ClubBooks American Airlines
- JAL Mileage BankBooks American Airlines
- Qantas Frequent FlyerBooks American Airlines
- Qatar Airways Privilege ClubBooks American Airlines
MSY to LEX with one stop
9 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Atlanta (ATL)Delta Air Lines the whole way




- Via Charlotte (CLT)American Airlines the whole way


- Via Chicago (ORD)American Airlines and United Airlines the whole way




- Via Detroit (DTW)Delta Air Lines the whole way


- Via Dallas (DFW)American Airlines the whole way



- Via Austin (AUS)Delta Air Lines the whole way



- Via Washington (DCA)American Airlines and Southwest Airlines, then Delta Air Lines



- Via Fort Lauderdale (FLL)JetBlue Airways and Southwest Airlines, then Allegiant Air



- Via Miami (MIA)American Airlines the whole way


MSY to LEX: common questions
Which airlines fly nonstop from MSY to LEX?
American Airlines (oneworld) flies nonstop from New Orleans (MSY) to Lexington (LEX).
How far is New Orleans from Lexington by plane?
New Orleans (MSY) and Lexington (LEX) are 644 miles (1,036 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book MSY to LEX award flights?
9 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, American AAdvantage, British Airways Club, Cathay Pacific Asia Miles, Finnair Plus, Iberia Club, JAL Mileage Bank, Qantas Frequent Flyer and 1 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does MSY to LEX cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MSY to LEX with taxes and fees.
Where can I connect between New Orleans and Lexington?
The most direct connections are through Atlanta (ATL), Charlotte (CLT), Chicago (ORD), Detroit (DTW) and Dallas (DFW). On 7 of them the same airline flies both flights, for example Delta Air Lines through Atlanta.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.