Milwaukee (MKE) to Saint Louis (STL) flights
One airline flies nonstop from Milwaukee (MKE) to Saint Louis (STL): Southwest Airlines. The two airports are 318 miles (511 km) apart. There are also 8 ways to fly it with one stop, through Chicago, Chicago and Kansas City and more.
Airlines flying nonstop from MKE to STL
- Southwest AirlinesNot in an allianceWho books it
MKE to STL with one stop
8 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Kansas City (MCI)Southwest Airlines the whole way
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Minneapolis (MSP)Delta Air Lines the whole way
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Charlotte (CLT)American Airlines the whole way
MKE to STL: common questions
Which airlines fly nonstop from MKE to STL?
Southwest Airlines flies nonstop from Milwaukee (MKE) to Saint Louis (STL).
How far is Milwaukee from Saint Louis by plane?
Milwaukee (MKE) and Saint Louis (STL) are 318 miles (511 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does MKE to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MKE to STL with taxes and fees.
Where can I connect between Milwaukee and Saint Louis?
The most direct connections are through Chicago (ORD), Chicago (MDW), Kansas City (MCI), Detroit (DTW) and Minneapolis (MSP). On 8 of them the same airline flies both flights, for example American Airlines through Chicago.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.