Chicago (MDW) to Buffalo (BUF) flights
One airline flies nonstop from Chicago (MDW) to Buffalo (BUF): Southwest Airlines. The two airports are 467 miles (751 km) apart. There are also 11 ways to fly it with one stop, through Detroit, Baltimore and Washington and more.
Airlines flying nonstop from MDW to BUF
- Southwest AirlinesNot in an allianceWho books it

MDW to BUF with one stop
11 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Detroit (DTW)Delta Air Lines the whole way




- Via Baltimore (BWI)Southwest Airlines the whole way


- Via Washington (DCA)Southwest Airlines, then American Airlines


- Via Philadelphia (PHL)Southwest Airlines, then American Airlines


- Via New York (LGA)Southwest Airlines, then Delta Air Lines and American Airlines



- Via Nashville (BNA)Southwest Airlines the whole way


- Via Minneapolis (MSP)Delta Air Lines and Southwest Airlines the whole way




- Via Raleigh/Durham (RDU)Southwest Airlines, then Frontier Airlines


- Via Charlotte (CLT)Southwest Airlines, then American Airlines


- Via Boston (BOS)Southwest Airlines, then JetBlue Airways, Delta Air Lines and 1 more




- Via Atlanta (ATL)Delta Air Lines and Frontier Airlines the whole way





MDW to BUF: common questions
Which airlines fly nonstop from MDW to BUF?
Southwest Airlines flies nonstop from Chicago (MDW) to Buffalo (BUF).
How far is Chicago from Buffalo by plane?
Chicago (MDW) and Buffalo (BUF) are 467 miles (751 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does MDW to BUF cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for MDW to BUF with taxes and fees.
Where can I connect between Chicago and Buffalo?
The most direct connections are through Detroit (DTW), Baltimore (BWI), Washington (DCA), Philadelphia (PHL) and New York (LGA). On 5 of them the same airline flies both flights, for example Delta Air Lines through Detroit.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.