La Serena (LSC) to Santiago (SCL) flights
3 airlines fly nonstop from La Serena (LSC) to Santiago (SCL): JetSMART, LATAM Airlines and Sky Airline. The two airports are 242 miles (389 km) apart. There are also 2 ways to fly it with one stop, through Concepcion and Antofagasta.
Airlines flying nonstop from LSC to SCL
- JetSMARTNot in an alliance
- LATAM AirlinesNot in an alliance · bookable with 3 programsWho books it
- Sky AirlineNot in an alliance
Book LSC to SCL with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Alaska Atmos RewardsBooks LATAM Airlines
- Delta SkyMilesBooks LATAM Airlines
- Virgin Atlantic Flying ClubBooks LATAM Airlines
LSC to SCL with one stop
2 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Concepcion (CCP)JetSMART the whole way
- Via Antofagasta (ANF)Sky Airline, JetSMART and 1 more the whole way
LSC to SCL: common questions
Which airlines fly nonstop from LSC to SCL?
JetSMART, LATAM Airlines and Sky Airline fly nonstop from La Serena (LSC) to Santiago (SCL).
How far is La Serena from Santiago by plane?
La Serena (LSC) and Santiago (SCL) are 242 miles (389 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book LSC to SCL award flights?
3 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, Delta SkyMiles and Virgin Atlantic Flying Club. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does LSC to SCL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for LSC to SCL with taxes and fees.
Where can I connect between La Serena and Santiago?
The most direct connections are through Concepcion (CCP) and Antofagasta (ANF). On 2 of them the same airline flies both flights, for example JetSMART through Concepcion.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.