Jacksonville (JAX) to Saint Louis (STL) flights
One airline flies nonstop from Jacksonville (JAX) to Saint Louis (STL): Southwest Airlines. The two airports are 754 miles (1,214 km) apart. There are also 24 ways to fly it with one stop, through Atlanta, Nashville and Charlotte and more.
Airlines flying nonstop from JAX to STL
- Southwest AirlinesNot in an allianceWho books it
JAX to STL with one stop
24 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Atlanta (ATL)Delta Air Lines and Frontier Airlines the whole way
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Columbus (CMH)Breeze Airways, then Southwest Airlines
- Via Raleigh/Durham (RDU)Breeze Airways, then Southwest Airlines
- Via Chicago (MDW)Southwest Airlines the whole way
- Via New Orleans (MSY)Breeze Airways, then Southwest Airlines
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Pittsburgh (PIT)Allegiant Air and Breeze Airways, then Southwest Airlines
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Dulles (IAD)United Airlines the whole way
- Via Norfolk (ORF)Breeze Airways, then Southwest Airlines
- Via Washington (DCA)American Airlines the whole way
- Via Fort Lauderdale (FLL)JetBlue Airways and Breeze Airways, then Southwest Airlines
- Via Baltimore (BWI)Southwest Airlines the whole way
JAX to STL: common questions
Which airlines fly nonstop from JAX to STL?
Southwest Airlines flies nonstop from Jacksonville (JAX) to Saint Louis (STL).
How far is Jacksonville from Saint Louis by plane?
Jacksonville (JAX) and Saint Louis (STL) are 754 miles (1,214 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does JAX to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for JAX to STL with taxes and fees.
Where can I connect between Jacksonville and Saint Louis?
The most direct connections are through Atlanta (ATL), Nashville (BNA), Charlotte (CLT), Columbus (CMH) and Raleigh/Durham (RDU). On 18 of them the same airline flies both flights, for example Delta Air Lines through Atlanta.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.