Guayaquil (GYE) to Santiago (SCL) flights
One airline flies nonstop from Guayaquil (GYE) to Santiago (SCL): LATAM Airlines. The two airports are 2,238 miles (3,602 km) apart. There are also 6 ways to fly it with one stop, through Lima, Quito and Bogota and more.
Airlines flying nonstop from GYE to SCL
- LATAM AirlinesNot in an alliance · bookable with 3 programsWho books it
Book GYE to SCL with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Alaska Atmos RewardsBooks LATAM Airlines
- Delta SkyMilesBooks LATAM Airlines
- Virgin Atlantic Flying ClubBooks LATAM Airlines
GYE to SCL with one stop
6 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Lima (LIM)LATAM Airlines the whole way
- Via Quito (UIO)LATAM Airlines the whole way
- Via Bogota (BOG)AVIANCA the whole way
- Via Buenos Aires (EZE)AVIANCA, then Sky Airline, KLM and 1 more
- Via Medellin (MDE)AVIANCA, then JetSMART
- Via Panama City (PTY)Copa Airlines the whole way
GYE to SCL: common questions
Which airlines fly nonstop from GYE to SCL?
LATAM Airlines flies nonstop from Guayaquil (GYE) to Santiago (SCL).
How far is Guayaquil from Santiago by plane?
Guayaquil (GYE) and Santiago (SCL) are 2,238 miles (3,602 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book GYE to SCL award flights?
3 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, Delta SkyMiles and Virgin Atlantic Flying Club. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does GYE to SCL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for GYE to SCL with taxes and fees.
Where can I connect between Guayaquil and Santiago?
The most direct connections are through Lima (LIM), Quito (UIO), Bogota (BOG), Buenos Aires (EZE) and Medellin (MDE). On 4 of them the same airline flies both flights, for example LATAM Airlines through Lima.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.