Panama City (ECP) to Chicago (MDW) flights
One airline flies nonstop from Panama City (ECP) to Chicago (MDW): Southwest Airlines. The two airports are 797 miles (1,283 km) apart. There are also 16 ways to fly it with one stop, through Nashville, Indianapolis and Atlanta and more.
Airlines flying nonstop from ECP to MDW
- Southwest AirlinesNot in an allianceWho books it

ECP to MDW with one stop
16 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way


- Via Indianapolis (IND)Southwest Airlines the whole way


- Via Atlanta (ATL)Delta Air Lines the whole way




- Via Saint Louis (STL)Southwest Airlines the whole way


- Via Milwaukee (MKE)Southwest Airlines the whole way


- Via Columbus (CMH)Southwest Airlines the whole way


- Via Charlotte (CLT)American Airlines, then Southwest Airlines


- Via Kansas City (MCI)Southwest Airlines the whole way


- Via Washington (DCA)American Airlines, then Southwest Airlines


- Via Baltimore (BWI)Southwest Airlines the whole way


- Via Dallas (DAL)Southwest Airlines the whole way


- Via Dallas (DFW)American Airlines, then Frontier Airlines


- Via Houston (HOU)Southwest Airlines the whole way


- Via Philadelphia (PHL)American Airlines, then Southwest Airlines


- Via Austin (AUS)Southwest Airlines the whole way



ECP to MDW: common questions
Which airlines fly nonstop from ECP to MDW?
Southwest Airlines flies nonstop from Panama City (ECP) to Chicago (MDW).
How far is Panama City from Chicago by plane?
Panama City (ECP) and Chicago (MDW) are 797 miles (1,283 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does ECP to MDW cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for ECP to MDW with taxes and fees.
Where can I connect between Panama City and Chicago?
The most direct connections are through Nashville (BNA), Indianapolis (IND), Atlanta (ATL), Saint Louis (STL) and Milwaukee (MKE). On 11 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.