Detroit (DTW) to Greenville (GSP) flights
One airline flies nonstop from Detroit (DTW) to Greenville (GSP): Delta Air Lines. The two airports are 510 miles (820 km) apart. Delta Air Lines is in SkyTeam. There are also 17 ways to fly it with one stop, through Columbus, Cincinnati and Charlotte and more.
Airlines flying nonstop from DTW to GSP
- Delta Air LinesSkyTeam · bookable with 8 programsWho books it
Book DTW to GSP with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Aeromexico RewardsBooks Delta Air Lines
- Air France-KLM Flying BlueBooks Delta Air Lines
- China Eastern Eastern MilesBooks Delta Air Lines
- Delta SkyMilesBooks Delta Air Lines
- Garuda Indonesia GarudaMilesBooks Delta Air Lines
- Korean Air SKYPASSBooks Delta Air Lines
- SAS EuroBonusBooks Delta Air Lines
- Virgin Atlantic Flying ClubBooks Delta Air Lines
DTW to GSP with one stop
17 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Columbus (CMH)Delta Air Lines, then Breeze Airways
- Via Cincinnati (CVG)Delta Air Lines, then Breeze Airways
- Via Charlotte (CLT)American Airlines the whole way
- Via Pittsburgh (PIT)Delta Air Lines, then Breeze Airways
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Dulles (IAD)United Airlines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Baltimore (BWI)Southwest Airlines the whole way
- Via Philadelphia (PHL)American Airlines the whole way
- Via New York (EWR)United Airlines the whole way
- Via New York (LGA)American Airlines and Delta Air Lines the whole way
- Via New Haven (HVN)Avelo Airlines the whole way
- Via Hartford (BDL)Delta Air Lines, then Breeze Airways
DTW to GSP: common questions
Which airlines fly nonstop from DTW to GSP?
Delta Air Lines (SkyTeam) flies nonstop from Detroit (DTW) to Greenville (GSP).
How far is Detroit from Greenville by plane?
Detroit (DTW) and Greenville (GSP) are 510 miles (820 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book DTW to GSP award flights?
8 programs can book at least one of the nonstop airlines: Aeromexico Rewards, Air France-KLM Flying Blue, China Eastern Eastern Miles, Delta SkyMiles, Garuda Indonesia GarudaMiles, Korean Air SKYPASS, SAS EuroBonus and Virgin Atlantic Flying Club. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does DTW to GSP cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for DTW to GSP with taxes and fees.
Where can I connect between Detroit and Greenville?
The most direct connections are through Columbus (CMH), Cincinnati (CVG), Charlotte (CLT), Pittsburgh (PIT) and Nashville (BNA). On 11 of them the same airline flies both flights, for example American Airlines through Charlotte.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.