Columbus (CMH) to Saint Louis (STL) flights
One airline flies nonstop from Columbus (CMH) to Saint Louis (STL): Southwest Airlines. The two airports are 409 miles (659 km) apart. There are also 20 ways to fly it with one stop, through Chicago, Chicago and Detroit and more.
Airlines flying nonstop from CMH to STL
- Southwest AirlinesNot in an allianceWho books it
CMH to STL with one stop
20 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Kansas City (MCI)Southwest Airlines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines, Southwest Airlines and 1 more the whole way
- Via Toronto (YYZ)Air Canada the whole way
- Via Dulles (IAD)United Airlines the whole way
- Via Raleigh/Durham (RDU)Breeze Airways, then Southwest Airlines
- Via Omaha (OMA)Southwest Airlines the whole way
- Via Washington (DCA)American Airlines and Southwest Airlines the whole way
- Via Minneapolis (MSP)Delta Air Lines the whole way
- Via Baltimore (BWI)Southwest Airlines the whole way
- Via Norfolk (ORF)Breeze Airways, then Southwest Airlines
CMH to STL: common questions
Which airlines fly nonstop from CMH to STL?
Southwest Airlines flies nonstop from Columbus (CMH) to Saint Louis (STL).
How far is Columbus from Saint Louis by plane?
Columbus (CMH) and Saint Louis (STL) are 409 miles (659 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does CMH to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for CMH to STL with taxes and fees.
Where can I connect between Columbus and Saint Louis?
The most direct connections are through Chicago (MDW), Chicago (ORD), Detroit (DTW), Nashville (BNA) and Kansas City (MCI). On 16 of them the same airline flies both flights, for example Southwest Airlines through Chicago.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.