Charlotte (CLT) to Saint Louis (STL) flights
2 airlines fly nonstop from Charlotte (CLT) to Saint Louis (STL): American Airlines and Southwest Airlines. The two airports are 575 miles (925 km) apart. American Airlines is in oneworld. There are also 34 ways to fly it with one stop, through Nashville, Atlanta and Columbus and more.
Airlines flying nonstop from CLT to STL
- American Airlinesoneworld · bookable with 9 programsWho books it
- Southwest AirlinesNot in an allianceWho books it
Book CLT to STL with points
Loyalty programs that can book at least one of the nonstop airlines, from the Award Booking Guide.
- Alaska Atmos RewardsBooks American Airlines
- American AAdvantageBooks American Airlines
- British Airways ClubBooks American Airlines
- Cathay Pacific Asia MilesBooks American Airlines
- Finnair PlusBooks American Airlines
- Iberia ClubBooks American Airlines
- JAL Mileage BankBooks American Airlines
- Qantas Frequent FlyerBooks American Airlines
- Qatar Airways Privilege ClubBooks American Airlines
CLT to STL with one stop
34 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Columbus (CMH)American Airlines, then Southwest Airlines
- Via Raleigh/Durham (RDU)American Airlines, then Southwest Airlines
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Charleston (CHS)American Airlines, then Southwest Airlines
- Via Myrtle Beach (MYR)American Airlines, then Southwest Airlines
- Via Savannah (SAV)American Airlines, then Southwest Airlines
- Via Cleveland (CLE)American Airlines, then Southwest Airlines
- Via Pittsburgh (PIT)American Airlines, then Southwest Airlines
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Milwaukee (MKE)American Airlines, then Southwest Airlines
- Via Dulles (IAD)United Airlines the whole way
- Via Kansas City (MCI)American Airlines, then Southwest Airlines
CLT to STL: common questions
Which airlines fly nonstop from CLT to STL?
American Airlines (oneworld) and Southwest Airlines fly nonstop from Charlotte (CLT) to Saint Louis (STL).
How far is Charlotte from Saint Louis by plane?
Charlotte (CLT) and Saint Louis (STL) are 575 miles (925 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
Which points programs can book CLT to STL award flights?
9 programs can book at least one of the nonstop airlines: Alaska Atmos Rewards, American AAdvantage, British Airways Club, Cathay Pacific Asia Miles, Finnair Plus, Iberia Club, JAL Mileage Bank, Qantas Frequent Flyer and 1 more. Which flights each can book depends on its partners, so check the airline before you transfer points.
How many miles does CLT to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for CLT to STL with taxes and fees.
Where can I connect between Charlotte and Saint Louis?
The most direct connections are through Nashville (BNA), Atlanta (ATL), Columbus (CMH), Raleigh/Durham (RDU) and Chicago (MDW). On 16 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.