Cleveland (CLE) to Saint Louis (STL) flights
One airline flies nonstop from Cleveland (CLE) to Saint Louis (STL): Southwest Airlines. The two airports are 487 miles (784 km) apart. There are also 15 ways to fly it with one stop, through Detroit, Chicago and Chicago and more.
Airlines flying nonstop from CLE to STL
- Southwest AirlinesNot in an allianceWho books it
CLE to STL with one stop
15 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Toronto (YYZ)Air Canada the whole way
- Via Dulles (IAD)United Airlines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines and Frontier Airlines the whole way
- Via Baltimore (BWI)Southwest Airlines the whole way
- Via Minneapolis (MSP)Delta Air Lines the whole way
- Via Raleigh/Durham (RDU)Frontier Airlines, then Southwest Airlines
- Via Philadelphia (PHL)American Airlines the whole way
- Via New York (EWR)United Airlines the whole way
- Via New York (LGA)American Airlines and Delta Air Lines the whole way
CLE to STL: common questions
Which airlines fly nonstop from CLE to STL?
Southwest Airlines flies nonstop from Cleveland (CLE) to Saint Louis (STL).
How far is Cleveland from Saint Louis by plane?
Cleveland (CLE) and Saint Louis (STL) are 487 miles (784 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does CLE to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for CLE to STL with taxes and fees.
Where can I connect between Cleveland and Saint Louis?
The most direct connections are through Detroit (DTW), Chicago (MDW), Chicago (ORD), Nashville (BNA) and Toronto (YYZ). On 14 of them the same airline flies both flights, for example Delta Air Lines through Detroit.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.