Charleston (CHS) to Saint Louis (STL) flights
One airline flies nonstop from Charleston (CHS) to Saint Louis (STL): Southwest Airlines. The two airports are 706 miles (1,137 km) apart. There are also 28 ways to fly it with one stop, through Nashville, Atlanta and Charlotte and more.
Airlines flying nonstop from CHS to STL
- Southwest AirlinesNot in an allianceWho books it
CHS to STL with one stop
28 connections, most direct first. 2-stop routings and flight times are in Routes with Pro.
- Via Nashville (BNA)Southwest Airlines the whole way
- Via Atlanta (ATL)Delta Air Lines the whole way
- Via Charlotte (CLT)American Airlines the whole way
- Via Columbus (CMH)Breeze Airways, then Southwest Airlines
- Via Chicago (MDW)Southwest Airlines the whole way
- Via Chicago (ORD)American Airlines and United Airlines the whole way
- Via Pittsburgh (PIT)Breeze Airways, then Southwest Airlines
- Via Detroit (DTW)Delta Air Lines the whole way
- Via Norfolk (ORF)Breeze Airways, then Southwest Airlines
- Via Dulles (IAD)United Airlines the whole way
- Via Washington (DCA)American Airlines the whole way
- Via Orlando (MCO)Breeze Airways, then Frontier Airlines and Southwest Airlines
- Via Baltimore (BWI)Southwest Airlines the whole way
- Via Tampa (TPA)Breeze Airways, then Southwest Airlines
- Via New Orleans (MSY)Breeze Airways, then Southwest Airlines
CHS to STL: common questions
Which airlines fly nonstop from CHS to STL?
Southwest Airlines flies nonstop from Charleston (CHS) to Saint Louis (STL).
How far is Charleston from Saint Louis by plane?
Charleston (CHS) and Saint Louis (STL) are 706 miles (1,137 km) apart along the great circle, the shortest path a flight can take. Connections add distance on top.
How many miles does CHS to STL cost?
It depends on the program: each prices the route from its own chart or dynamically. The Award Flight Pricer compares 30+ programs for CHS to STL with taxes and fees.
Where can I connect between Charleston and Saint Louis?
The most direct connections are through Nashville (BNA), Atlanta (ATL), Charlotte (CLT), Columbus (CMH) and Chicago (MDW). On 19 of them the same airline flies both flights, for example Southwest Airlines through Nashville.
More routes
Routes are scheduled nonstop flights. The route data is refreshed monthly; this list was last checked November 11, 2026. Seasonal routes and new launches can be missing or end early, so confirm with the airline before you book. Distances are great-circle, the shortest path between the two airports.